Difference between revisions of "3-ISOPROPYLMALDEHYDROG-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=XMPXAN-RXN XMPXAN-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** probable_cytosolic_imp-gm...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-ISOPROPYLMALDEHYDROG-RXN 3-ISOPROPYLMALDEHYDROG-RXN] == * direction: ** REVERSIBLE * common name:...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=XMPXAN-RXN XMPXAN-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-ISOPROPYLMALDEHYDROG-RXN 3-ISOPROPYLMALDEHYDROG-RXN] ==
 
* direction:
 
* direction:
−
** LEFT-TO-RIGHT
+
** REVERSIBLE
 
* common name:
 
* common name:
−
** probable_cytosolic_imp-gmp_specific_5_-nucleotidase
+
** 3-isopropylmalate dehydrogenase
−
** 5_deoxy_cytosolic_type_c_protein
+
−
** ORF
+
−
** 5_-nucleotidase
+
−
* ec number:
+
−
** [http://enzyme.expasy.org/EC/3.1.3.5 EC-3.1.3.5]
+
 
* Synonym(s):
 
* Synonym(s):
 +
** β-isopropylmalic enzyme
 +
** threo-Ds-3-isopropylmalate dehydrogenase
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[XANTHOSINE-5-PHOSPHATE]][c] '''+''' 1 [[WATER]][c] '''=>''' 1 [[XANTHOSINE]][c] '''+''' 1 [[Pi]][c]
+
** 1 [[NAD]][c] '''+''' 1 [[2-D-THREO-HYDROXY-3-CARBOXY-ISOCAPROATE]][c] '''<=>''' 1 [[NADH]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[CPD-7100]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 XMP[c] '''+''' 1 H2O[c] '''=>''' 1 xanthosine[c] '''+''' 1 phosphate[c]
+
** 1 NAD+[c] '''+''' 1 (2R,3S)-3-isopropylmalate[c] '''<=>''' 1 NADH[c] '''+''' 1 H+[c] '''+''' 1 (2S)-2-isopropyl-3-oxosuccinate[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* Gene: [[Tiso_gene_14435]]
+
* Gene: [[Tiso_gene_2920]]
−
** Source: [[annotation-in-silico_annotation]]
+
** Source: [[annotation-experimental_annotation]]
−
*** Assignment: EC-NUMBER
+
−
* Gene: [[Tiso_gene_6640]]
+
−
** Source: [[orthology-esiliculosus]]
+
−
* Gene: [[Tiso_gene_14434]]
+
−
** Source: [[annotation-in-silico_annotation]]
+
−
*** Assignment: EC-NUMBER
+
−
* Gene: [[Tiso_gene_13929]]
+
−
** Source: [[annotation-in-silico_annotation]]
+
−
*** Assignment: EC-NUMBER
+
−
** Source: [[orthology-esiliculosus]]
+
−
* Gene: [[Tiso_gene_5911]]
+
−
** Source: [[annotation-in-silico_annotation]]
+
−
*** Assignment: AUTOMATED-NAME-MATCH
+
−
* Gene: [[Tiso_gene_14246]]
+
−
** Source: [[annotation-in-silico_annotation]]
+
−
*** Assignment: EC-NUMBER
+
−
* Gene: [[Tiso_gene_6988]]
+
−
** Source: [[annotation-in-silico_annotation]]
+
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-athaliana]]
 +
** Source: [[orthology-synechocystis]]
 
** Source: [[orthology-esiliculosus]]
 
** Source: [[orthology-esiliculosus]]
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-5695]], urate biosynthesis/inosine 5'-phosphate degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5695 PWY-5695]
+
* [[LEUSYN-PWY]], L-leucine biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=LEUSYN-PWY LEUSYN-PWY]
−
** '''4''' reactions found over '''4''' reactions in the full pathway
+
** '''6''' reactions found over '''6''' reactions in the full pathway
−
* [[PWY-6596]], adenosine nucleotides degradation I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6596 PWY-6596]
+
* [[PWY-6871]], 3-methylbutanol biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6871 PWY-6871]
−
** '''8''' reactions found over '''8''' reactions in the full pathway
+
** '''6''' reactions found over '''7''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[orthology]]
 
* Category: [[orthology]]
 +
** Source: [[orthology-athaliana]]
 +
*** Tool: [[pantograph]]
 +
** Source: [[orthology-synechocystis]]
 +
*** Tool: [[pantograph]]
 
** Source: [[orthology-esiliculosus]]
 
** Source: [[orthology-esiliculosus]]
 
*** Tool: [[pantograph]]
 
*** Tool: [[pantograph]]
 
* Category: [[annotation]]
 
* Category: [[annotation]]
−
** Source: [[annotation-in-silico_annotation]]
+
** Source: [[annotation-experimental_annotation]]
 
*** Tool: [[pathwaytools]]
 
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=28530 28530]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10892 10892]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R02719 R02719]
+
** [http://www.genome.jp/dbget-bin/www_bget?R04426 R04426]
−
{{#set: direction=LEFT-TO-RIGHT}}
+
* UNIPROT:
−
{{#set: common name=probable_cytosolic_imp-gmp_specific_5_-nucleotidase}}
+
** [http://www.uniprot.org/uniprot/P05644 P05644]
−
{{#set: common name=5_deoxy_cytosolic_type_c_protein}}
+
** [http://www.uniprot.org/uniprot/P05645 P05645]
−
{{#set: common name=ORF}}
+
** [http://www.uniprot.org/uniprot/Q01987 Q01987]
−
{{#set: common name=5_-nucleotidase}}
+
** [http://www.uniprot.org/uniprot/Q00412 Q00412]
−
{{#set: ec number=EC-3.1.3.5}}
+
** [http://www.uniprot.org/uniprot/P08791 P08791]
−
{{#set: gene associated=Tiso_gene_14435|Tiso_gene_6640|Tiso_gene_14434|Tiso_gene_13929|Tiso_gene_5911|Tiso_gene_14246|Tiso_gene_6988}}
+
** [http://www.uniprot.org/uniprot/P30125 P30125]
−
{{#set: in pathway=PWY-5695|PWY-6596}}
+
** [http://www.uniprot.org/uniprot/Q9PLW0 Q9PLW0]
 +
** [http://www.uniprot.org/uniprot/O66607 O66607]
 +
** [http://www.uniprot.org/uniprot/P12010 P12010]
 +
** [http://www.uniprot.org/uniprot/P04173 P04173]
 +
** [http://www.uniprot.org/uniprot/Q5SIY4 Q5SIY4]
 +
** [http://www.uniprot.org/uniprot/P24098 P24098]
 +
** [http://www.uniprot.org/uniprot/Q9JU79 Q9JU79]
 +
** [http://www.uniprot.org/uniprot/P43860 P43860]
 +
** [http://www.uniprot.org/uniprot/P41019 P41019]
 +
** [http://www.uniprot.org/uniprot/P54354 P54354]
 +
** [http://www.uniprot.org/uniprot/Q56268 Q56268]
 +
** [http://www.uniprot.org/uniprot/P29102 P29102]
 +
** [http://www.uniprot.org/uniprot/P37412 P37412]
 +
** [http://www.uniprot.org/uniprot/P23390 P23390]
 +
** [http://www.uniprot.org/uniprot/P29696 P29696]
 +
** [http://www.uniprot.org/uniprot/P41766 P41766]
 +
** [http://www.uniprot.org/uniprot/Q02143 Q02143]
 +
** [http://www.uniprot.org/uniprot/P34733 P34733]
 +
** [http://www.uniprot.org/uniprot/P50180 P50180]
 +
** [http://www.uniprot.org/uniprot/Q12591 Q12591]
 +
** [http://www.uniprot.org/uniprot/Q12590 Q12590]
 +
** [http://www.uniprot.org/uniprot/Q12592 Q12592]
 +
** [http://www.uniprot.org/uniprot/P07139 P07139]
 +
** [http://www.uniprot.org/uniprot/P41926 P41926]
 +
** [http://www.uniprot.org/uniprot/P48012 P48012]
 +
** [http://www.uniprot.org/uniprot/P87256 P87256]
 +
** [http://www.uniprot.org/uniprot/P87257 P87257]
 +
** [http://www.uniprot.org/uniprot/P73960 P73960]
 +
** [http://www.uniprot.org/uniprot/O86504 O86504]
 +
** [http://www.uniprot.org/uniprot/O85837 O85837]
 +
** [http://www.uniprot.org/uniprot/P18869 P18869]
 +
** [http://www.uniprot.org/uniprot/P34738 P34738]
 +
{{#set: direction=REVERSIBLE}}
 +
{{#set: common name=3-isopropylmalate dehydrogenase}}
 +
{{#set: common name=&beta;-isopropylmalic enzyme|threo-Ds-3-isopropylmalate dehydrogenase}}
 +
{{#set: gene associated=Tiso_gene_2920}}
 +
{{#set: in pathway=LEUSYN-PWY|PWY-6871}}
 
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction category=orthology|annotation}}
−
{{#set: reconstruction source=annotation-in-silico_annotation|orthology-esiliculosus}}
+
{{#set: reconstruction source=orthology-athaliana|annotation-experimental_annotation|orthology-synechocystis|orthology-esiliculosus}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 19:39, 21 March 2018

Reaction 3-ISOPROPYLMALDEHYDROG-RXN

  • direction:
    • REVERSIBLE
  • common name:
    • 3-isopropylmalate dehydrogenase
  • Synonym(s):
    • β-isopropylmalic enzyme
    • threo-Ds-3-isopropylmalate dehydrogenase

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • LEUSYN-PWY, L-leucine biosynthesis: LEUSYN-PWY
    • 6 reactions found over 6 reactions in the full pathway
  • PWY-6871, 3-methylbutanol biosynthesis (engineered): PWY-6871
    • 6 reactions found over 7 reactions in the full pathway

Reconstruction information

External links





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