Difference between revisions of "RXN-12705"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-7706 RXN-7706] == * direction: ** LEFT-TO-RIGHT * common name: ** polyketide_synthase ** ORF *...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-12705 RXN-12705] == * direction: ** LEFT-TO-RIGHT * common name: ** hydroxyacyl-coenzyme_a_dehy...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-7706 RXN-7706] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-12705 RXN-12705] ==
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
** polyketide_synthase
+
** hydroxyacyl-coenzyme_a_dehydrogenase_3-ketoacyl-coenzyme_a_thiolase_enoyl-coenzyme_a_hydratasealpha_subunit
** ORF
+
** 3-hydroxyacyl-_dehydrogenase
 +
** hydroxyacyl-coenzyme_a_mitochondrial
 
* ec number:
 
* ec number:
** [http://enzyme.expasy.org/EC/1.1.1.1 EC-1.1.1.1]
+
** [http://enzyme.expasy.org/EC/1.1.1.35 EC-1.1.1.35]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
** 1 [[NADH]][c] '''+''' 1 [[CPD-7036]][c] '''+''' 1 [[PROTON]][c] '''=>''' 1 [[NAD]][c] '''+''' 1 [[CPD-7037]][c]
+
** 1 [[NAD]][c] '''+''' 1 [[CPD-13694]][c] '''=>''' 1 [[CPD-13695]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[NADH]][c]
 
* With common name(s):
 
* With common name(s):
** 1 NADH[c] '''+''' 1 3-methylthiopropanal[c] '''+''' 1 H+[c] '''=>''' 1 NAD+[c] '''+''' 1 methionol[c]
+
** 1 NAD+[c] '''+''' 1 24-hydroxy-3-oxocholest-4-en-26-oyl-CoA[c] '''=>''' 1 3,24-dioxocholest-4-en-26-oyl-CoA[c] '''+''' 1 H+[c] '''+''' 1 NADH[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
* Gene: [[Tiso_gene_5424]]
+
* Gene: [[Tiso_gene_18839]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
* Gene: [[Tiso_gene_5425]]
+
* Gene: [[Tiso_gene_5857]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
* Gene: [[Tiso_gene_6562]]
+
** Source: [[annotation-experimental_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-esiliculosus]]
 +
* Gene: [[Tiso_gene_14026]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
* Gene: [[Tiso_gene_7649]]
+
** Source: [[annotation-experimental_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-esiliculosus]]
 +
* Gene: [[Tiso_gene_18838]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
* Gene: [[Tiso_gene_6563]]
+
* Gene: [[Tiso_gene_14027]]
 +
** Source: [[orthology-esiliculosus]]
 +
* Gene: [[Tiso_gene_14262]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[annotation-experimental_annotation]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 
== Pathways  ==
 
== Pathways  ==
* [[PWY-5082]], L-methionine degradation III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5082 PWY-5082]
+
* [[PWY-6946]], cholesterol degradation to androstenedione II (cholesterol dehydrogenase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6946 PWY-6946]
** '''1''' reactions found over '''3''' reactions in the full pathway
+
** '''3''' reactions found over '''22''' reactions in the full pathway
 +
* [[PWY-6945]], cholesterol degradation to androstenedione I (cholesterol oxidase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6945 PWY-6945]
 +
** '''2''' reactions found over '''17''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 +
* Category: [[orthology]]
 +
** Source: [[orthology-esiliculosus]]
 +
*** Tool: [[pantograph]]
 
* Category: [[annotation]]
 
* Category: [[annotation]]
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Tool: [[pathwaytools]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
*** Tool: [[pathwaytools]]
 
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
{{#set: common name=polyketide_synthase}}
+
{{#set: common name=hydroxyacyl-coenzyme_a_dehydrogenase_3-ketoacyl-coenzyme_a_thiolase_enoyl-coenzyme_a_hydratasealpha_subunit}}
{{#set: common name=ORF}}
+
{{#set: common name=3-hydroxyacyl-_dehydrogenase}}
{{#set: ec number=EC-1.1.1.1}}
+
{{#set: common name=hydroxyacyl-coenzyme_a_mitochondrial}}
{{#set: gene associated=Tiso_gene_5424|Tiso_gene_5425|Tiso_gene_6562|Tiso_gene_7649|Tiso_gene_6563}}
+
{{#set: ec number=EC-1.1.1.35}}
{{#set: in pathway=PWY-5082}}
+
{{#set: gene associated=Tiso_gene_18839|Tiso_gene_5857|Tiso_gene_14026|Tiso_gene_18838|Tiso_gene_14027|Tiso_gene_14262}}
{{#set: reconstruction category=annotation}}
+
{{#set: in pathway=PWY-6946|PWY-6945}}
{{#set: reconstruction source=annotation-in-silico_annotation}}
+
{{#set: reconstruction category=orthology|annotation}}
{{#set: reconstruction tool=pathwaytools}}
+
{{#set: reconstruction source=annotation-experimental_annotation|annotation-in-silico_annotation|orthology-esiliculosus}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:59, 21 March 2018

Reaction RXN-12705

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • hydroxyacyl-coenzyme_a_dehydrogenase_3-ketoacyl-coenzyme_a_thiolase_enoyl-coenzyme_a_hydratasealpha_subunit
    • 3-hydroxyacyl-_dehydrogenase
    • hydroxyacyl-coenzyme_a_mitochondrial
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 NAD+[c] + 1 24-hydroxy-3-oxocholest-4-en-26-oyl-CoA[c] => 1 3,24-dioxocholest-4-en-26-oyl-CoA[c] + 1 H+[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6946, cholesterol degradation to androstenedione II (cholesterol dehydrogenase): PWY-6946
    • 3 reactions found over 22 reactions in the full pathway
  • PWY-6945, cholesterol degradation to androstenedione I (cholesterol oxidase): PWY-6945
    • 2 reactions found over 17 reactions in the full pathway

Reconstruction information

External links