Difference between revisions of "RXN-12037"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=ACYL-COA-OXIDASE-RXN ACYL-COA-OXIDASE-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** acyl-...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-12037 RXN-12037] == * direction: ** LEFT-TO-RIGHT * common name: ** 3',5'-diiodothyronine 5'-de...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=ACYL-COA-OXIDASE-RXN ACYL-COA-OXIDASE-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-12037 RXN-12037] ==
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
−
** acyl-coenzyme_a_oxidase
+
** 3',5'-diiodothyronine 5'-deiodinase
 +
** type_i_iodothyronine_deiodinase
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/1.3.3.6 EC-1.3.3.6]
+
** [http://enzyme.expasy.org/EC/1.21.99.4 EC-1.21.99.4]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[ACYL-COA]][c] '''+''' 1 [[OXYGEN-MOLECULE]][c] '''=>''' 1 [[HYDROGEN-PEROXIDE]][c] '''+''' 1 [[TRANS-D2-ENOYL-COA]][c]
+
** 1 [[Donor-H2]][c] '''+''' 1 [[CPD-13008]][c] '''=>''' 1 [[CPD-387]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[CPD-13010]][c] '''+''' 1 [[Acceptor]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 an acyl-CoA[c] '''+''' 1 oxygen[c] '''=>''' 1 hydrogen peroxide[c] '''+''' 1 a trans-2-enoyl-CoA[c]
+
** 1 a reduced electron acceptor[c] '''+''' 1 3',5'-diiodothyronine[c] '''=>''' 1 iodide[c] '''+''' 1 H+[c] '''+''' 1 3'-monoiodothyronine[c] '''+''' 1 an oxidized electron acceptor[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* Gene: [[Tiso_gene_18566]]
+
* Gene: [[Tiso_gene_20481]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
** Source: [[orthology-esiliculosus]]
 
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-7007]], methyl ketone biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7007 PWY-7007]
+
* [[PWY-6260]], thyroid hormone metabolism I (via deiodination): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6260 PWY-6260]
−
** '''3''' reactions found over '''6''' reactions in the full pathway
+
** '''3''' reactions found over '''12''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* Category: [[orthology]]
 
−
** Source: [[orthology-esiliculosus]]
 
−
*** Tool: [[pantograph]]
 
 
* Category: [[annotation]]
 
* Category: [[annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
*** Tool: [[pathwaytools]]
 
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
−
* PIR:
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T52121 T52121]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T52120 T52120]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T04418 T04418]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S64224 S64224]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S40722 S40722]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=OXRTA2 OXRTA2]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=OXRTA1 OXRTA1]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=OXCKX5 OXCKX5]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=OXCKX4 OXCKX4]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=OXCKX OXCKX]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=OXCKPM OXCKPM]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=OXCKP2 OXCKP2]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=OXCKAX OXCKAX]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JC4563 JC4563]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=I38095 I38095]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=B54942 B54942]
 
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A54942 A54942]
 
−
* LIGAND-RXN:
 
−
** [http://www.genome.jp/dbget-bin/www_bget?R00388 R00388]
 
−
* UNIPROT:
 
−
** [http://www.uniprot.org/uniprot/Q15067 Q15067]
 
−
** [http://www.uniprot.org/uniprot/Q00468 Q00468]
 
−
** [http://www.uniprot.org/uniprot/P06598 P06598]
 
−
** [http://www.uniprot.org/uniprot/P11356 P11356]
 
−
** [http://www.uniprot.org/uniprot/P07872 P07872]
 
−
** [http://www.uniprot.org/uniprot/P34355 P34355]
 
−
** [http://www.uniprot.org/uniprot/P13711 P13711]
 
−
** [http://www.uniprot.org/uniprot/O23977 O23977]
 
−
** [http://www.uniprot.org/uniprot/O65201 O65201]
 
−
** [http://www.uniprot.org/uniprot/O65202 O65202]
 
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
−
{{#set: common name=acyl-coenzyme_a_oxidase}}
+
{{#set: common name=3',5'-diiodothyronine 5'-deiodinase}}
−
{{#set: ec number=EC-1.3.3.6}}
+
{{#set: common name=type_i_iodothyronine_deiodinase}}
−
{{#set: gene associated=Tiso_gene_18566}}
+
{{#set: ec number=EC-1.21.99.4}}
−
{{#set: in pathway=PWY-7007}}
+
{{#set: gene associated=Tiso_gene_20481}}
−
{{#set: reconstruction category=orthology|annotation}}
+
{{#set: in pathway=PWY-6260}}
−
{{#set: reconstruction source=annotation-in-silico_annotation|orthology-esiliculosus}}
+
{{#set: reconstruction category=annotation}}
−
{{#set: reconstruction tool=pantograph|pathwaytools}}
+
{{#set: reconstruction source=annotation-in-silico_annotation}}
 +
{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 21:19, 21 March 2018

Reaction RXN-12037

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • 3',5'-diiodothyronine 5'-deiodinase
    • type_i_iodothyronine_deiodinase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 a reduced electron acceptor[c] + 1 3',5'-diiodothyronine[c] => 1 iodide[c] + 1 H+[c] + 1 3'-monoiodothyronine[c] + 1 an oxidized electron acceptor[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6260, thyroid hormone metabolism I (via deiodination): PWY-6260
    • 3 reactions found over 12 reactions in the full pathway

Reconstruction information

External links

Retrieved from "http://gem-aureme.irisa.fr/tisogem/index.php?title=RXN-12037&oldid=47830"