Difference between revisions of "RXN-8975"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=1.2.4.4-RXN 1.2.4.4-RXN] == * direction: ** REVERSIBLE * common name: ** 3-methyl-2-oxobutanoate_de...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-8975 RXN-8975] == * direction: ** REVERSIBLE * common name: ** ORF * ec number: ** [http://enzy...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=1.2.4.4-RXN 1.2.4.4-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-8975 RXN-8975] ==
 
* direction:
 
* direction:
 
** REVERSIBLE
 
** REVERSIBLE
 
* common name:
 
* common name:
−
** 3-methyl-2-oxobutanoate_dehydrogenase
+
** ORF
−
** 2-oxoisovalerate_dehydrogenase_alpha_subunit_mitochondrial
+
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/1.2.4.4 EC-1.2.4.4]
+
** [http://enzyme.expasy.org/EC/2.7.8.13 EC-2.7.8.13]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[BCAA-dehydrogenase-lipoyl]][c] '''+''' 1 [[2-KETO-ISOVALERATE]][c] '''+''' 1 [[PROTON]][c] '''<=>''' 1 [[BCAA-dehydrogenase-2MP-DH-lipoyl]][c] '''+''' 1 [[CARBON-DIOXIDE]][c]
+
** 1 [[CPD-9646]][c] '''+''' 1 [[C3]][c] '''<=>''' 1 [[C4]][c] '''+''' 1 [[UMP]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 an [apo BCAA dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] '''+''' 1 3-methyl-2-oxobutanoate[c] '''+''' 1 H+[c] '''<=>''' 1 an [apo BCAA dehydrogenase E2 protein] N6-S-[2-methylpropanoyl]dihydrolipoyl-L-lysine[c] '''+''' 1 CO2[c]
+
** 1 di-trans,octa-cis-undecaprenyl phosphate[c] '''+''' 1 UDP-N-acetyl-&alpha;-D-muramoyl-L-alanyl-&gamma;-D-glutamyl-L-lysyl-D-alanyl-D-alanine[c] '''<=>''' 1 undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-&gamma;-D-glutamyl-L-lysyl- D-alanyl-D-alanine[c] '''+''' 1 UMP[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* Gene: [[Tiso_gene_11793]]
+
* Gene: [[Tiso_gene_1604]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
−
*** Assignment: AUTOMATED-NAME-MATCH
 
−
* Gene: [[Tiso_gene_3260]]
 
−
** Source: [[annotation-in-silico_annotation]]
 
−
*** Assignment: EC-NUMBER
 
−
** Source: [[annotation-experimental_annotation]]
 
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
* Gene: [[Tiso_gene_18084]]
 
 
** Source: [[orthology-esiliculosus]]
 
** Source: [[orthology-esiliculosus]]
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-5046]], 2-oxoisovalerate decarboxylation to isobutanoyl-CoA: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5046 PWY-5046]
+
* [[PWY-6471]], peptidoglycan biosynthesis IV (Enterococcus faecium): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6471 PWY-6471]
−
** '''3''' reactions found over '''3''' reactions in the full pathway
+
** '''3''' reactions found over '''10''' reactions in the full pathway
 +
* [[PWY-5265]], peptidoglycan biosynthesis II (staphylococci): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5265 PWY-5265]
 +
** '''3''' reactions found over '''10''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[orthology]]
 
* Category: [[orthology]]
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* Category: [[annotation]]
 
* Category: [[annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
−
*** Tool: [[pathwaytools]]
 
−
** Source: [[annotation-experimental_annotation]]
 
 
*** Tool: [[pathwaytools]]
 
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 +
* RHEA:
 +
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21920 21920]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R01701 R01701]
+
** [http://www.genome.jp/dbget-bin/www_bget?R05629 R05629]
−
* UNIPROT:
+
−
** [http://www.uniprot.org/uniprot/P21839 P21839]
+
−
** [http://www.uniprot.org/uniprot/P21953 P21953]
+
−
** [http://www.uniprot.org/uniprot/P37940 P37940]
+
−
** [http://www.uniprot.org/uniprot/Q9PK54 Q9PK54]
+
−
** [http://www.uniprot.org/uniprot/P37941 P37941]
+
−
** [http://www.uniprot.org/uniprot/P11178 P11178]
+
−
** [http://www.uniprot.org/uniprot/P12694 P12694]
+
−
** [http://www.uniprot.org/uniprot/P09061 P09061]
+
−
** [http://www.uniprot.org/uniprot/P09060 P09060]
+
−
** [http://www.uniprot.org/uniprot/P11960 P11960]
+
−
** [http://www.uniprot.org/uniprot/O84344 O84344]
+
−
** [http://www.uniprot.org/uniprot/Q9Z9E8 Q9Z9E8]
+
−
** [http://www.uniprot.org/uniprot/Q9I1M2 Q9I1M2]
+
−
** [http://www.uniprot.org/uniprot/P35738 P35738]
+
−
** [http://www.uniprot.org/uniprot/P50136 P50136]
+
−
** [http://www.uniprot.org/uniprot/O48615 O48615]
+
−
** [http://www.uniprot.org/uniprot/O03849 O03849]
+
−
** [http://www.uniprot.org/uniprot/Q53592 Q53592]
+
−
** [http://www.uniprot.org/uniprot/Q53593 Q53593]
+
−
** [http://www.uniprot.org/uniprot/O82450 O82450]
+
 
{{#set: direction=REVERSIBLE}}
 
{{#set: direction=REVERSIBLE}}
−
{{#set: common name=3-methyl-2-oxobutanoate_dehydrogenase}}
+
{{#set: common name=ORF}}
−
{{#set: common name=2-oxoisovalerate_dehydrogenase_alpha_subunit_mitochondrial}}
+
{{#set: ec number=EC-2.7.8.13}}
−
{{#set: ec number=EC-1.2.4.4}}
+
{{#set: gene associated=Tiso_gene_1604}}
−
{{#set: gene associated=Tiso_gene_11793|Tiso_gene_3260|Tiso_gene_18084}}
+
{{#set: in pathway=PWY-6471|PWY-5265}}
−
{{#set: in pathway=PWY-5046}}
+
 
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction category=orthology|annotation}}
−
{{#set: reconstruction source=annotation-in-silico_annotation|annotation-experimental_annotation|orthology-esiliculosus}}
+
{{#set: reconstruction source=annotation-in-silico_annotation|orthology-esiliculosus}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:20, 21 March 2018

Reaction RXN-8975

  • direction:
    • REVERSIBLE
  • common name:
    • ORF
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 di-trans,octa-cis-undecaprenyl phosphate[c] + 1 UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine[c] <=> 1 undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine[c] + 1 UMP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6471, peptidoglycan biosynthesis IV (Enterococcus faecium): PWY-6471
    • 3 reactions found over 10 reactions in the full pathway
  • PWY-5265, peptidoglycan biosynthesis II (staphylococci): PWY-5265
    • 3 reactions found over 10 reactions in the full pathway

Reconstruction information

External links





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