PWY-7269

Reaction PYRUVATE-CARBOXYLASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • ORF
  • Pyruvate carboxylase
• ec number:
  • EC-6.4.1.1
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 HCO3[c] + 1 PYRUVATE[c] + 1 ATP[c] => 1 PROTON[c] + 1 Pi[c] + 1 OXALACETIC_ACID[c] + 1 ADP[c]
• With common name(s):
  • 1 hydrogencarbonate[c] + 1 pyruvate[c] + 1 ATP[c] => 1 H+[c] + 1 phosphate[c] + 1 oxaloacetate[c] + 1 ADP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_15144
  • IN-SILICO_ANNOTATION
    • AUTOMATED-NAME-MATCH
• Tiso_gene_2812
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • EXPERIMENTAL_ANNOTATION
    • EC-NUMBER
  • pantograph-esiliculosus
• Tiso_gene_15145
  • IN-SILICO_ANNOTATION
    • AUTOMATED-NAME-MATCH

Pathways

• PWY-6142, gluconeogenesis II (Methanobacterium thermoautotrophicum): PWY-6142
  • 8 reactions found over 14 reactions in the full pathway
• PWY-6146, Methanobacterium thermoautotrophicum biosynthetic metabolism: PWY-6146
  • 7 reactions found over 16 reactions in the full pathway
• PWY-5750, itaconate biosynthesis: PWY-5750
  • 3 reactions found over 4 reactions in the full pathway
• P42-PWY, incomplete reductive TCA cycle: P42-PWY
  • 4 reactions found over 7 reactions in the full pathway
• PWY66-399, gluconeogenesis III: PWY66-399
  • 10 reactions found over 12 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: manual
  • Source: manual-primary_network
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 20844
• LIGAND-RXN:
  • R00344
• UNIPROT:
  • Q05920
  • Q9PNQ4
  • P95127
  • Q9PP00
  • Q9CHQ7
  • Q9KWU4
  • P11498
  • P52873
  • P11154
  • P32327
  • O17732
  • Q9UUE1
  • Q16921
  • Q9XBJ1