HISTCYCLOHYD-RXN

Reaction RXN-12710

• direction:
  • LEFT-TO-RIGHT
• common name:
  • acetyl-_c-acetyltransferase
  • 3-ketoacyl-_thiolase
  • thiolase
• ec number:
  • EC-2.3.1.16
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CPD-13699[c] + 1 CO-A[c] => 1 CPD-13700[c] + 1 ACETYL-COA[c]
• With common name(s):
  • 1 3,22-dioxochol-4-en-24-oyl-CoA[c] + 1 coenzyme A[c] => 1 3-oxo-4-pregnene-20-carboxyl-CoA[c] + 1 acetyl-CoA[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_15327
  • EXPERIMENTAL_ANNOTATION
    • EC-NUMBER
• Tiso_gene_3855
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • EXPERIMENTAL_ANNOTATION
    • EC-NUMBER
• Tiso_gene_3856
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_10116
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • EXPERIMENTAL_ANNOTATION
    • EC-NUMBER
• Tiso_gene_17451
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • EXPERIMENTAL_ANNOTATION
    • EC-NUMBER

Pathways

• PWY-6948, sitosterol degradation to androstenedione: PWY-6948
  • 2 reactions found over 18 reactions in the full pathway
• PWY-6946, cholesterol degradation to androstenedione II (cholesterol dehydrogenase): PWY-6946
  • 3 reactions found over 22 reactions in the full pathway
• PWY-6945, cholesterol degradation to androstenedione I (cholesterol oxidase): PWY-6945
  • 2 reactions found over 17 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools