RXN-5341

Reaction GLUTAMATE-DEHYDROGENASE-RXN

• direction:
  • REVERSIBLE
• common name:
  • glu_leu_phe_val_dehydrogenase
• ec number:
  • EC-1.4.1.2
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 GLT[c] + 1 NAD[c] + 1 WATER[c] <=> 1 2-KETOGLUTARATE[c] + 1 PROTON[c] + 1 NADH[c] + 1 AMMONIUM[c]
• With common name(s):
  • 1 L-glutamate[c] + 1 NAD+[c] + 1 H2O[c] <=> 1 2-oxoglutarate[c] + 1 H+[c] + 1 NADH[c] + 1 ammonium[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_2337
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • pantograph-esiliculosus

Pathways

• GLUTAMATE-DEG1-PWY, L-glutamate degradation I: GLUTAMATE-DEG1-PWY
  • 1 reactions found over 1 reactions in the full pathway
• PWY-6728, methylaspartate cycle: PWY-6728
  • 11 reactions found over 18 reactions in the full pathway
• P162-PWY, L-glutamate degradation V (via hydroxyglutarate): P162-PWY
  • 4 reactions found over 11 reactions in the full pathway
• PWY-5022, 4-aminobutanoate degradation V: PWY-5022
  • 3 reactions found over 7 reactions in the full pathway
• ALACAT2-PWY, L-alanine degradation II (to D-lactate): ALACAT2-PWY
  • 2 reactions found over 3 reactions in the full pathway
• PWY-7126, ethylene biosynthesis IV (engineered): PWY-7126
  • 1 reactions found over 3 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • esiliculosus
• annotation:
  • pathwaytools:
    • in-silico_annotation

External links

• RHEA:
  • 15133
• LIGAND-RXN:
  • R00243
• UNIPROT:
  • P20016
  • P28997
  • P41755
  • Q9JTP6
  • P00365
  • P93541
  • P80319
  • P24295
  • P27346
  • P33327
  • Q43260
  • O04937
  • Q25415
  • O74024
  • O59650