L-3-HYDROXYACYL-COA

Reaction RXN-9623

• direction:
  • LEFT-TO-RIGHT
• common name:
  • polyketide_synthase
  • ORF
  • long_chain_acyl-_synthetase
  • acyl-_synthetase
• ec number:
  • EC-6.2.1.3
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 ATP[c] + 1 PALMITATE[c] + 1 CO-A[c] => 1 PPI[c] + 1 PALMITYL-COA[c] + 1 AMP[c]
• With common name(s):
  • 1 ATP[c] + 1 palmitate[c] + 1 coenzyme A[c] => 1 diphosphate[c] + 1 palmitoyl-CoA[c] + 1 AMP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_9394
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-athaliana
  • Source: orthology-esiliculosus
  • Source: orthology-creinhardtii
• Gene: Tiso_gene_13394
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_12275
  • Source: orthology-creinhardtii
• Gene: Tiso_gene_10876
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_7855
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_348
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-athaliana
• Gene: Tiso_gene_136
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_135
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_500
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_4191
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-athaliana

Pathways

• PWY-5972, stearate biosynthesis I (animals and fungi): PWY-5972
  • 4 reactions found over 6 reactions in the full pathway
• PWY-5971, palmitate biosynthesis II (bacteria and plants): PWY-5971
  • 31 reactions found over 31 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-athaliana
    • Tool: pantograph
  • Source: orthology-creinhardtii
    • Tool: pantograph
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 30754
• LIGAND-RXN:
  • R01280