PHE

Reaction RXN-13158

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 3-isopropylmalate dehydrogenase
• ec number:
  • EC-1.1.1.85
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 2-D-THREO-HYDROXY-3-CARBOXY-ISOCAPROATE[c] + 1 NAD[c] => 1 2K-4CH3-PENTANOATE[c] + 1 NADH[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 (2R,3S)-3-isopropylmalate[c] + 1 NAD+[c] => 1 4-methyl-2-oxopentanoate[c] + 1 NADH[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_2920
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-esiliculosus

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: manual
  • Source: manual-primary_network
• Category: annotation
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 32272