Manual-reactions pwy-6475 tiso add

Reaction 3.5.2.17-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 5-hydroxyisourate_hydrolase
• ec number:
  • EC-3.5.2.17
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 5-HYDROXYISOURATE[c] + 1 WATER[c] => 1 CPD-5821[c] + 1 PROTON[c]
• With common name(s):
  • 1 5-hydroxyisourate[c] + 1 H2O[c] => 1 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_13181
  • Source: annotation-in-silico_annotation
    • Assignment: AUTOMATED-NAME-MATCH
  • Source: orthology-creinhardtii

Pathways

• PWY-7394, urate degradation to allantoin II: PWY-7394
  • 2 reactions found over 3 reactions in the full pathway
• PWY-5691, urate degradation to allantoin I: PWY-5691
  • 2 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-creinhardtii
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 23736
• LIGAND-RXN:
  • R06601