RXN-12508

Reaction RXN-12508

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 2-(α-hydroxyethyl)-TPP:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine acetyltransferase
  • ORF
  • pyruvate_dehydrogenase_e1_component_subunit_alpha-_mitochondrial
  • dihydrolipoamide_acetyltransferase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 Pyruvate-dehydrogenase-lipoate[c] + 1 2-ALPHA-HYDROXYETHYL-THPP[c] => 1 Pyruvate-dehydrogenase-acetylDHlipoyl[c] + 1 THIAMINE-PYROPHOSPHATE[c]
• With common name(s):
  • 1 a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] + 1 2-(α-hydroxyethyl)thiamine diphosphate[c] => 1 a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine[c] + 1 thiamine diphosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_17539
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_7519
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_6983
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_2693
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_2515
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-esiliculosus

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• LIGAND-RXN:
  • R03270

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