PWY0-1544

Reaction RXN-5901

• direction:
  • LEFT-TO-RIGHT
• common name:
  • polyketide_synthase
• ec number:
  • EC-1.1.1.36
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 ACETOACETYL-COA[c] + 1 PROTON[c] + 1 NADPH[c] => 1 NADP[c] + 1 CPD-650[c]
• With common name(s):
  • 1 acetoacetyl-CoA[c] + 1 H+[c] + 1 NADPH[c] => 1 NADP+[c] + 1 (3R)-3-hydroxybutanoyl-CoA[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_6563
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_10876
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_6562
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_500
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_5425
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_136
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_5424
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_13394
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_135
  • IN-SILICO_ANNOTATION
    • EC-NUMBER

Pathways

• PWY-5741, ethylmalonyl-CoA pathway: PWY-5741
  • 2 reactions found over 11 reactions in the full pathway
• PWY1-3, polyhydroxybutanoate biosynthesis: PWY1-3
  • 2 reactions found over 3 reactions in the full pathway
• PWY-7216, (R)- and (S)-3-hydroxybutanoate biosynthesis (engineered): PWY-7216
  • 3 reactions found over 5 reactions in the full pathway
• PWY-5676, acetyl-CoA fermentation to butanoate II: PWY-5676
  • 2 reactions found over 7 reactions in the full pathway

Reconstruction information

• annotation:
  • pathwaytools:
    • in-silico_annotation

External links

• LIGAND-RXN:
  • R01977