L-phenylalanyl-L-lysyl-Protein

Reaction RXN0-949

• direction:
  • LEFT-TO-RIGHT
• common name:
  • lipoyl_synthase_mitochondrial
  • lipoyl_mitochondrial
• ec number:
  • EC-2.8.1.8
• Synonym(s):

Reaction Formula

• With identifiers:
  • 2 Sulfurated-Sulfur-Acceptors[c] + 1 Octanoylated-domains[c] + 2 Reduced-2Fe-2S-Ferredoxins[c] + 2 S-ADENOSYLMETHIONINE[c] => 2 MET[c] + 1 Lipoyl-Protein-N6-lipoyllysine[c] + 2 CH33ADO[c] + 2 Unsulfurated-Sulfur-Acceptors[c] + 2 Oxidized-2Fe-2S-Ferredoxins[c]
• With common name(s):
  • 2 a sulfurated [sulfur carrier][c] + 1 a [lipoyl-carrier protein] N6-octanoyl-L-lysine[c] + 2 a reduced [2Fe-2S] ferredoxin[c] + 2 S-adenosyl-L-methionine[c] => 2 L-methionine[c] + 1 a [lipoyl-carrier protein]-N6-lipoyl-L-lysine[c] + 2 5'-deoxyadenosine[c] + 2 an unsulfurated [sulfur carrier][c] + 2 an oxidized [2Fe-2S] ferredoxin[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_8049
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_437
  • IN-SILICO_ANNOTATION
    • EC-NUMBER

Pathways

• PWY-6987, lipoate biosynthesis and incorporation III (Bacillus): PWY-6987
  • 2 reactions found over 3 reactions in the full pathway
• PWY0-1275, lipoate biosynthesis and incorporation II: PWY0-1275
  • 2 reactions found over 2 reactions in the full pathway
• PWY0-501, lipoate biosynthesis and incorporation I: PWY0-501
  • 2 reactions found over 2 reactions in the full pathway

Reconstruction information

• annotation:
  • pathwaytools:
    • in-silico_annotation

External links

• LIGAND-RXN:
  • R07767