PWY-6281

Reaction MRNA-GUANINE-N7--METHYLTRANSFERASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • mrna_capguanine-n7methyltransferase
  • mrna_cap_guanine-n7_methyltransferase
• ec number:
  • EC-2.1.1.56
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 G5-pppR-mRNAs[c] + 1 S-ADENOSYLMETHIONINE[c] => 1 PROTON[c] + 1 m7G5-pppR-mRNAs[c] + 1 ADENOSYL-HOMO-CYS[c]
• With common name(s):
  • 1 a 5'-(5'-triphosphoguanosine)-purine-[mRNA][c] + 1 S-adenosyl-L-methionine[c] => 1 H+[c] + 1 a 5'-(N7-methyl 5'-triphosphoguanosine)-(purine-ribonucleotide)-[mRNA][c] + 1 S-adenosyl-L-homocysteine[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_5135
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_2105
  • IN-SILICO_ANNOTATION
    • AUTOMATED-NAME-MATCH
• Tiso_gene_5134
  • IN-SILICO_ANNOTATION
    • EC-NUMBER

Pathways

• PWY-7375, mRNA capping I: PWY-7375
  • 2 reactions found over 3 reactions in the full pathway

Reconstruction information

• annotation:
  • pathwaytools:
    • in-silico_annotation

External links

• LIGAND-RXN:
  • R03805
• UNIPROT:
  • Q66121
  • Q9I8S2
  • P03588
  • Q00020
  • P06011
  • P20122
  • P28726
  • P28931
  • P04298
  • P04318
  • P20979
  • Q98257
  • Q98268
  • P03589