3-OXOACYL-ACP-SYNTH-RXN

Reaction RXN-9537

• direction:
  • LEFT-TO-RIGHT
• common name:
  • polyketide_synthase
• ec number:
  • EC-2.3.1.86
  • EC-2.3.1.85
  • EC-4.2.1.59
• Synonym(s):
  • (3R)-hydroxymyristoyl-ACP dehydratase

Reaction Formula

• With identifiers:
  • 1 R-3-hydroxymyristoyl-ACPs[c] => 1 Tetradec-2-enoyl-ACPs[c] + 1 WATER[c]
• With common name(s):
  • 1 a (3R)-3-hydroxymyristoyl-[acp][c] => 1 a trans tetradec-2-enoyl-[acp][c] + 1 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_6885
  • pantograph-synechocystis
• Tiso_gene_10876
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_500
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_136
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_13394
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_135
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_6884
  • EXPERIMENTAL_ANNOTATION
    • AUTOMATED-NAME-MATCH
• Tiso_gene_9421
  • pantograph-creinhardtii
• Tiso_gene_6671
  • pantograph-creinhardtii

Pathways

• PWY-5971, palmitate biosynthesis II (bacteria and plants): PWY-5971
  • 31 reactions found over 31 reactions in the full pathway
• PWY-5994, palmitate biosynthesis I (animals and fungi): PWY-5994
  • 31 reactions found over 31 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • creinhardtii
    • synechocystis
• manual:
  • primary_network
• annotation:
  • pathwaytools:
    • experimental_annotation
    • in-silico_annotation