SUCCCOASYN-RXN

Reaction RXN-11373

• direction:
  • LEFT-TO-RIGHT
• common name:
  • diphthamide synthase
  • diphthine_synthase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 3-carboxy-3-dimethylammonio-propyl-L-his[c] + 1 S-ADENOSYLMETHIONINE[c] => 1 ADENOSYL-HOMO-CYS[c] + 1 PROTON[c] + 1 DIPHTINE[c]
• With common name(s):
  • 1 a 2-[(3S)-3-carboxy-3-(dimethylammonio)propyl]-L-histidine-[translation elongation factor 2][c] + 1 S-adenosyl-L-methionine[c] => 1 S-adenosyl-L-homocysteine[c] + 1 H+[c] + 1 a diphthine-[translation elongation factor 2][c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_15743
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • pantograph-esiliculosus

Reconstruction information

• orthology:
  • pantograph:
    • esiliculosus
• annotation:
  • pathwaytools:
    • in-silico_annotation

External links

• LIGAND-RXN:
  • R08469