RXN-13299

Reaction CHOLESTENONE-5-ALPHA-REDUCTASE-RXN

• direction:
  • REVERSIBLE
• common name:
  • 3-oxo-5-alpha-steroid_4-dehydrogenase
• ec number:
  • EC-1.3.1.22
• Synonym(s):
  • 3-oxosteroid Δ4-dehydrogenase
  • Δ4-3-ketosteroid 5α-oxidoreductase

Reaction Formula

• With identifiers:
  • 1 NADP[c] + 1 CPD-1081[c] <=> 1 NADPH[c] + 1 PROTON[c] + 1 CPD-323[c]
• With common name(s):
  • 1 NADP+[c] + 1 5α-cholestan-3-one[c] <=> 1 NADPH[c] + 1 H+[c] + 1 cholest-4-en-3-one[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_14327
  • IN-SILICO_ANNOTATION
    • AUTOMATED-NAME-MATCH

Reconstruction information

• annotation:
  • pathwaytools:
    • in-silico_annotation

External links

• RHEA:
  • 24552
• LIGAND-RXN:
  • R02610
• UNIPROT:
  • P31214
  • P31213