Tiso gene 13619

Reaction RXN-13158

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 3-isopropylmalate dehydrogenase
• ec number:
  • EC-1.1.1.85
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 2-D-THREO-HYDROXY-3-CARBOXY-ISOCAPROATE[c] => 1 2K-4CH3-PENTANOATE[c] + 1 NADH[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 NAD+[c] + 1 (2R,3S)-3-isopropylmalate[c] => 1 4-methyl-2-oxopentanoate[c] + 1 NADH[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_2920
  • EXPERIMENTAL_ANNOTATION
    • EC-NUMBER
  • pantograph-esiliculosus

Reconstruction information

• orthology:
  • pantograph:
    • esiliculosus
• manual:
  • primary_network
• annotation:
  • pathwaytools:
    • experimental_annotation

External links

• RHEA:
  • 32272