CPD-11665

Reaction 3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 3-hydroxyisobutyrate_mitochondrial
  • 3-hydroxyisobutyrate_dehydrogenase
  • uncharacterized_oxidoreductase
• ec number:
  • EC-1.1.1.31
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 CPD-12175[c] => 1 NADH[c] + 1 CH3-MALONATE-S-ALD[c] + 1 PROTON[c]
• With common name(s):
  • 1 NAD+[c] + 1 (S)-3-hydroxy-isobutanoate[c] => 1 NADH[c] + 1 (S)-methylmalonate-semialdehyde[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_19590
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • pantograph-esiliculosus
  • pantograph-creinhardtii
• Tiso_gene_5857
  • pantograph-athaliana
  • pantograph-creinhardtii
• Tiso_gene_19771
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_7107
  • IN-SILICO_ANNOTATION
    • AUTOMATED-NAME-MATCH
• Tiso_gene_19772
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • EXPERIMENTAL_ANNOTATION
    • EC-NUMBER
• Tiso_gene_19592
  • pantograph-esiliculosus
  • pantograph-creinhardtii

Pathways

• VALDEG-PWY, L-valine degradation I: VALDEG-PWY
  • 8 reactions found over 8 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • creinhardtii
    • esiliculosus
    • athaliana
• annotation:
  • pathwaytools:
    • experimental_annotation
    • in-silico_annotation

External links

• LIGAND-RXN:
  • R02047
• UNIPROT:
  • P29266
  • P28811
  • Q8XAE4
  • Q55702
  • Q9XTI0