PWY-5497

Reaction RXN66-343

• direction:
  • LEFT-TO-RIGHT
• common name:
  • testosterone reductase
  • 3-oxo-5-alpha-steroid_4-dehydrogenase
• ec number:
  • EC-1.3.1.22
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PROTON[c] + 1 NADPH[c] + 1 TESTOSTERONE[c] => 1 17-BETA-HYDROXY-5ALPHA-ANDROSTAN-3-O[c] + 1 NADP[c]
• With common name(s):
  • 1 H+[c] + 1 NADPH[c] + 1 testosterone[c] => 1 17-β-hydroxy-5-α-androstan-3-one[c] + 1 NADP+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_14327
  • IN-SILICO_ANNOTATION
    • AUTOMATED-NAME-MATCH

Pathways

• PWY66-378, androgen biosynthesis: PWY66-378
  • 2 reactions found over 6 reactions in the full pathway

Reconstruction information

• annotation:
  • pathwaytools:
    • in-silico_annotation