CPD-14422

Reaction 2.4.1.225-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • exostosin-1
• ec number:
  • EC-2.4.1.225
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 GlcNAc-GlcA-Gal-Gal-Xyl-Protein[c] + 1 UDP-GLUCURONATE[c] => 1 GlcA-GlcNAc-GlcA-Gal-Gal-Xyl-Protein[c] + 1 UDP[c] + 1 PROTON[c]
• With common name(s):
  • 1 a [protein]-3-O-(α-D-GlcNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-serine[c] + 1 UDP-α-D-glucuronate[c] => 1 a [protein]-3-O-(β-D-GlcA-(1→3)-α-D-GlcNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-serine[c] + 1 UDP[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_6495
  • IN-SILICO_ANNOTATION
    • EC-NUMBER

Pathways

• PWY-6558, heparan sulfate biosynthesis (late stages): PWY-6558
  • 3 reactions found over 13 reactions in the full pathway

Reconstruction information

• annotation:
  • pathwaytools:
    • in-silico_annotation

External links

• LIGAND-RXN:
  • R07335