RXN-12399

Reaction PEPDEPHOS-RXN

• direction:
  • REVERSIBLE
• common name:
  • pyruvate_kinase
• ec number:
  • EC-2.7.1.40
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PYRUVATE[c] + 1 ATP[c] <=> 1 ADP[c] + 1 PHOSPHO-ENOL-PYRUVATE[c] + 1 PROTON[c]
• With common name(s):
  • 1 pyruvate[c] + 1 ATP[c] <=> 1 ADP[c] + 1 phosphoenolpyruvate[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_14504
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_18206
  • EXPERIMENTAL_ANNOTATION
    • EC-NUMBER
  • pantograph-esiliculosus
• Tiso_gene_974
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • EXPERIMENTAL_ANNOTATION
    • EC-NUMBER
  • pantograph-athaliana
  • pantograph-athaliana
  • pantograph-synechocystis
  • pantograph-esiliculosus
  • pantograph-creinhardtii
  • pantograph-creinhardtii
  • pantograph-creinhardtii
• Tiso_gene_14505
  • IN-SILICO_ANNOTATION
    • EC-NUMBER

Pathways

• PWY-1042, glycolysis IV (plant cytosol): PWY-1042
  • 9 reactions found over 10 reactions in the full pathway
• P341-PWY, glycolysis V (Pyrococcus): P341-PWY
  • 6 reactions found over 9 reactions in the full pathway
• PWY-2221, Entner-Doudoroff pathway III (semi-phosphorylative): PWY-2221
  • 5 reactions found over 9 reactions in the full pathway
• GLYCOLYSIS, glycolysis I (from glucose 6-phosphate): GLYCOLYSIS
  • 12 reactions found over 12 reactions in the full pathway
• NPGLUCAT-PWY, Entner-Doudoroff pathway II (non-phosphorylative): NPGLUCAT-PWY
  • 4 reactions found over 9 reactions in the full pathway
• ANAGLYCOLYSIS-PWY, glycolysis III (from glucose): ANAGLYCOLYSIS-PWY
  • 10 reactions found over 10 reactions in the full pathway
• PWY-7218, photosynthetic 3-hydroxybutanoate biosynthesis (engineered): PWY-7218
  • 7 reactions found over 10 reactions in the full pathway
• PWY-6901, superpathway of glucose and xylose degradation: PWY-6901
  • 8 reactions found over 12 reactions in the full pathway
• PWY-7383, anaerobic energy metabolism (invertebrates, cytosol): PWY-7383
  • 5 reactions found over 7 reactions in the full pathway
• P124-PWY, Bifidobacterium shunt: P124-PWY
  • 11 reactions found over 15 reactions in the full pathway
• PWY-6886, 1-butanol autotrophic biosynthesis (engineered): PWY-6886
  • 8 reactions found over 11 reactions in the full pathway
• PWY-5723, Rubisco shunt: PWY-5723
  • 10 reactions found over 10 reactions in the full pathway
• FERMENTATION-PWY, mixed acid fermentation: FERMENTATION-PWY
  • 9 reactions found over 16 reactions in the full pathway
• PWY-6142, gluconeogenesis II (Methanobacterium thermoautotrophicum): PWY-6142
  • 8 reactions found over 14 reactions in the full pathway
• P122-PWY, heterolactic fermentation: P122-PWY
  • 14 reactions found over 18 reactions in the full pathway
• PWY-5484, glycolysis II (from fructose 6-phosphate): PWY-5484
  • 11 reactions found over 11 reactions in the full pathway
• PWY-7003, glycerol degradation to butanol: PWY-7003
  • 8 reactions found over 10 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-athaliana
    • Tool: pantograph
  • Source: orthology-creinhardtii
    • Tool: pantograph
  • Source: orthology-synechocystis
    • Tool: pantograph
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: manual
  • Source: manual-primary_network
• Category: annotation
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 18157
• LIGAND-RXN:
  • R00200
• UNIPROT:
  • Q7M034
  • P11979
  • P11980
  • Q07637
  • P34038
  • P43924
  • Q57572
  • P0AD61
  • P19680
  • Q9PIB0
  • P80885
  • Q9UYU6
  • Q9JWX8
  • P47458
  • Q46078
  • P30614
  • P22200
  • Q27788
  • P51182
  • P51181
  • P31865
  • P00549
  • P00548
  • P30613
  • O75758
  • P12928
  • O30853
  • P30615
  • P30616
  • Q02499
  • P22360
  • P21599
  • P14618
  • Q42954
  • Q40545
  • P52480
  • P52489
  • P78031
  • Q55863
  • P73534
  • O65595
  • Q42806
  • Q43117
  • Q10208