RXN-9527

Reaction PRPPAMIDOTRANS-RXN

• direction:
  • REVERSIBLE
• common name:
  • ORF
  • short-chain_dehydrogenase_reductase
• ec number:
  • EC-2.4.2.14
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 GLT[c] + 1 PPI[c] + 1 5-P-BETA-D-RIBOSYL-AMINE[c] <=> 1 PRPP[c] + 1 WATER[c] + 1 GLN[c]
• With common name(s):
  • 1 L-glutamate[c] + 1 diphosphate[c] + 1 5-phospho-β-D-ribosylamine[c] <=> 1 5-phospho-α-D-ribose 1-diphosphate[c] + 1 H2O[c] + 1 L-glutamine[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_1007
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_9914
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-athaliana
  • Source: orthology-synechocystis
  • Source: orthology-esiliculosus
  • Source: orthology-creinhardtii

Pathways

• PWY-6121, 5-aminoimidazole ribonucleotide biosynthesis I: PWY-6121
  • 5 reactions found over 5 reactions in the full pathway
• PWY-6122, 5-aminoimidazole ribonucleotide biosynthesis II: PWY-6122
  • 4 reactions found over 5 reactions in the full pathway
• PWY-7282, 4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis (yeast): PWY-7282
  • 6 reactions found over 9 reactions in the full pathway
• PWY-6277, superpathway of 5-aminoimidazole ribonucleotide biosynthesis: PWY-6277
  • 6 reactions found over 9 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-athaliana
    • Tool: pantograph
  • Source: orthology-creinhardtii
    • Tool: pantograph
  • Source: orthology-synechocystis
    • Tool: pantograph
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: manual
  • Source: manual-primary_network
• Category: annotation
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 14905
• LIGAND-RXN:
  • R01072
• UNIPROT:
  • P28173
  • P35433
  • Q06203
  • O29388
  • O67236
  • P65829
  • O57979
  • Q9X0X4
  • Q9RXT6
  • Q9K0C4
  • Q9V253
  • Q9PIT3
  • Q57657
  • Q9JVC9
  • O26742
  • P43854
  • P35853
  • P41390
  • Q27601
  • Q38999
  • P04046
  • Q55621
  • Q55038
  • Q9STG9
  • Q9T0J5
  • P52418
  • P52419
  • Q22134
  • Q9ZB05
  • P00497
  • P0AG16