CPD-17365

Reaction BRANCHED-CHAINAMINOTRANSFERLEU-RXN

• direction:
  • REVERSIBLE
• common name:
  • branched-chain_amino_acid_aminotransferase
• ec number:
  • EC-2.6.1.6
  • EC-2.6.1.42
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 LEU[c] + 1 2-KETOGLUTARATE[c] <=> 1 GLT[c] + 1 2K-4CH3-PENTANOATE[c]
• With common name(s):
  • 1 L-leucine[c] + 1 2-oxoglutarate[c] <=> 1 L-glutamate[c] + 1 4-methyl-2-oxopentanoate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_18403
  • Source: orthology-synechocystis
• Gene: Tiso_gene_14984
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-synechocystis
  • Source: orthology-esiliculosus

Pathways

• LEU-DEG2-PWY, L-leucine degradation I: LEU-DEG2-PWY
  • 6 reactions found over 6 reactions in the full pathway
• PWY-7767, leucine degradation IV: PWY-7767
  • 1 reactions found over 5 reactions in the full pathway
• LEUSYN-PWY, L-leucine biosynthesis: LEUSYN-PWY
  • 6 reactions found over 6 reactions in the full pathway
• PWY-5076, L-leucine degradation III: PWY-5076
  • 2 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-synechocystis
    • Tool: pantograph
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: manual
  • Source: manual-primary_network
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 18321
• LIGAND-RXN:
  • R01090
• UNIPROT:
  • Q9PIM6
  • P38891
  • P47176
  • O86505
  • O14370
  • O32954
  • P0AB80