PWY-6140

Reaction METHYLCROTONYL-COA-CARBOXYLASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial
  • propionyl-_carboxylase_alpha_chain
• ec number:
  • EC-6.4.1.4
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 3-METHYL-CROTONYL-COA[c] + 1 ATP[c] + 1 HCO3[c] => 1 PROTON[c] + 1 TRANS-3-METHYL-GLUTACONYL-COA[c] + 1 ADP[c] + 1 Pi[c]
• With common name(s):
  • 1 3-methylcrotonyl-CoA[c] + 1 ATP[c] + 1 hydrogencarbonate[c] => 1 H+[c] + 1 3-methylglutaconyl-CoA[c] + 1 ADP[c] + 1 phosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_14499
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-athaliana
  • Source: orthology-creinhardtii
• Gene: Tiso_gene_5029
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-creinhardtii
• Gene: Tiso_gene_10675
  • Source: annotation-in-silico_annotation
    • Assignment: AUTOMATED-NAME-MATCH

Pathways

• LEU-DEG2-PWY, L-leucine degradation I: LEU-DEG2-PWY
  • 6 reactions found over 6 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-athaliana
    • Tool: pantograph
  • Source: orthology-creinhardtii
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 13589
• LIGAND-RXN:
  • R04138
• UNIPROT:
  • Q40121
  • Q42777