4.1.99.4-RXN

Reaction ARGSUCCINSYN-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • argininosuccinate_synthase
• ec number:
  • EC-6.3.4.5
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 L-CITRULLINE[c] + 1 ATP[c] + 1 L-ASPARTATE[c] => 1 PROTON[c] + 1 AMP[c] + 1 PPI[c] + 1 L-ARGININO-SUCCINATE[c]
• With common name(s):
  • 1 L-citrulline[c] + 1 ATP[c] + 1 L-aspartate[c] => 1 H+[c] + 1 AMP[c] + 1 diphosphate[c] + 1 L-arginino-succinate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_12592
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-athaliana
  • Source: orthology-synechocystis
  • Source: orthology-esiliculosus
  • Source: orthology-creinhardtii

Pathways

• PWY-4984, urea cycle: PWY-4984
  • 5 reactions found over 5 reactions in the full pathway
• ARGSYN-PWY, L-arginine biosynthesis I (via L-ornithine): ARGSYN-PWY
  • 5 reactions found over 6 reactions in the full pathway
• PWY-5154, L-arginine biosynthesis III (via N-acetyl-L-citrulline): PWY-5154
  • 7 reactions found over 9 reactions in the full pathway
• ARGSYNBSUB-PWY, L-arginine biosynthesis II (acetyl cycle): ARGSYNBSUB-PWY
  • 9 reactions found over 9 reactions in the full pathway
• PWY-4983, L-citrulline-nitric oxide cycle: PWY-4983
  • 2 reactions found over 3 reactions in the full pathway
• PWY-7400, L-arginine biosynthesis IV (archaebacteria): PWY-7400
  • 7 reactions found over 9 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-athaliana
    • Tool: pantograph
  • Source: orthology-creinhardtii
    • Tool: pantograph
  • Source: orthology-synechocystis
    • Tool: pantograph
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: manual
  • Source: manual-primary_network
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 10932
• LIGAND-RXN:
  • R01954
• UNIPROT:
  • P22768
  • P0A6E4
  • P00966
  • P16460
  • P13256
  • P13257
  • P09034
  • P24532
  • Q9PHK7
  • P57799
  • Q60174
  • P44315
  • Q9JWM1
  • P50986
  • Q06734
  • P0C1A1
  • Q59491