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	Common name	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
1.1.1.8-RXN	ORF Glycerol-3-phosphate dehydrogenase	EC-1.1.1.8	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 13013 Tiso gene 15777 Tiso gene 6069 Tiso gene 2810 Tiso gene 2811 Tiso gene 3718	PWY-6118 PWY-7385 PWY-7411
1.1.3.37-RXN	ORF Xylitol oxidase Mitochondrial l-galactono- -lactone dehydrogenase	EC-1.1.3.37	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 14187 Tiso gene 6787 Tiso gene 210	PWY3O-6
1.1.3.41-RXN	Xylitol oxidase	EC-1.1.3.41	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 14187
1.1.4.1-RXN	Vitamin k epoxide reductase complex	EC-1.17.4.4	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 11760
1.10.2.2-RXN	Cytochrome b6-fcomplexiron-sulfurchloroplastic Ubiquinol-cytochrome c reductase Probable mitochondrial-processingpeptidasesubunitbeta	EC-1.10.2.2	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 7235 Tiso gene 9627 Tiso gene 4973 Tiso gene 18330 Tiso gene 15926	PWY-7279 PWY-7082 PWY-3781
1.11.1.12-RXN		EC-1.11.1.12	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation		PWY-4081
1.11.1.15-RXN	Alpha beta hydrolase fold protein Peroxiredoxin	EC-1.11.1.15	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 10066 Tiso gene 2589
1.13.11.6-RXN	3-hydroxyanthranilate 3,4-dioxygenase	EC-1.13.11.6	Annotation	Pathwaytools	Annotation-experimental annotation	Tiso gene 10922	PWY-5651 PWY-5647 PWY-6309 PWY-6505
1.14.11.18-RXN	Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	EC-1.14.11.18	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 16200 Tiso gene 561 Tiso gene 14450 Tiso gene 14707 Tiso gene 13319
1.14.11.19-RXN			Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 3330
1.14.11.2-RXN	Prolyl 4-hydroxylase ORF	EC-1.14.11.2	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9165 Tiso gene 16122 Tiso gene 17919 Tiso gene 18235 Tiso gene 15594 Tiso gene 9455 Tiso gene 18208 Tiso gene 1468 Tiso gene 13008 Tiso gene 8652 Tiso gene 4246 Tiso gene 3021 Tiso gene 9227 Tiso gene 17593 Tiso gene 292 Tiso gene 9873 Tiso gene 9035 Tiso gene 6296 Tiso gene 9636 Tiso gene 16842 Tiso gene 19638 Tiso gene 18933 Tiso gene 2158 Tiso gene 18145 Tiso gene 15328 Tiso gene 18689 Tiso gene 2280 Tiso gene 17823
1.14.13.70-RXN		EC-1.14.13.70	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 8263	PWY-2541
1.14.13.78-RXN	Ent-kaurene 19-hydroxylase		Orthology	Pantograph	Orthology-athaliana	Tiso gene 1547 Tiso gene 8263	PWY-5047 PWY-5034
1.14.13.79-RXN	Ent-kaurenoate monooxygenase		Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 8263 Tiso gene 3577	PWY-5047 PWY-5034
1.14.13.8-RXN	ORF Fad-containing monooxygenase	EC-1.14.13.8	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9613 Tiso gene 4 Tiso gene 9139 Tiso gene 10094
1.14.19.1-RXN		EC-1.14.19.1	Orthology	Pantograph	Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 1497 Tiso gene 9580 Tiso gene 8027 Tiso gene 18056 Tiso gene 19322 Tiso gene 7427 Tiso gene 19215	PWY-5996
1.14.19.3-RXN		EC-1.14.19.3	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 2508	PWY-6000
1.14.21.6-RXN		EC-1.14.19.20	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 5446	PWY66-341 PWY66-3
1.18.1.2-RXN	Ferredoxin--nadp embryochloroplastic Ferredoxin--nadp root isozyme chloroplastic	EC-1.18.1.2	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 20054 Tiso gene 19031 Tiso gene 17381 Tiso gene 17170 Tiso gene 20055 Tiso gene 20168	PWY-7230 PWY-101
1.2.1.13-RXN	Glyceraldehyde-3-phosphate dehydrogenase	EC-1.2.1.13	Manual Annotation	Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation	Tiso gene 6765 Tiso gene 20000 Tiso gene 10646 Tiso gene 6766	CALVIN-PWY
1.2.1.25-RXN	3-methyl-2-oxobutanoate dehydrogenase	EC-1.2.1.25	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 11793 Tiso gene 3260	VALDEG-PWY
1.2.1.27-RXN	Methylmalonate-semialdehyde dehydrogenase	EC-1.2.1.27	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 11323	PWY-5642
1.2.1.31-RXN	Polyketide synthase ORF	EC-1.2.1.31	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6563 Tiso gene 16719 Tiso gene 5425 Tiso gene 5424 Tiso gene 6562	LYSINE-DEG1-PWY
1.2.1.65-RXN		EC-1.2.1.65	Annotation	Pathwaytools	Annotation-in-silico annotation		PWY-5427
1.2.4.4-RXN	3-methyl-2-oxobutanoate dehydrogenase 2-oxoisovalerate dehydrogenase alpha subunit mitochondrial	EC-1.2.4.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 18084 Tiso gene 11793 Tiso gene 3260	PWY-5046
1.21.3.1-RXN		EC-1.21.3.1	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 3330	PWY-5629
1.3.1.20-RXN	Dihydrodiol dehydrogenase	EC-1.3.1.20	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 10406
1.3.1.9-RXN		EC-1.3.1.9	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 10778
1.3.7.3-RXN		EC-1.3.7.3	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 17350	PWY-5915 PWY-7579
1.3.7.4-RXN		EC-1.3.7.4	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 17350	PWY-7170
1.3.99.23-RXN	Carotenoid isomerase Carotene isomerase Fad nad -binding oxidoreductase domain-containing protein Carotenoid isomerase-like protein All-trans- -dihydroretinol saturase ORF	EC-1.3.99.23	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 13369 Tiso gene 9534 Tiso gene 3092 Tiso gene 917 Tiso gene 13367 Tiso gene 16795 Tiso gene 16794
1.3.99.5-RXN	3-oxo-5-alpha-steroid 4-dehydrogenase	EC-1.3.1.22	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 14327
1.4.3.19-RXN		EC-1.4.3.19	Orthology	Pantograph	Orthology-synechocystis	Tiso gene 16652 Tiso gene 13537 Tiso gene 11756	PWY-7396
1.5.1.19-RXN		EC-1.5.1.19	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 8893
1.5.1.20-RXN	Methylenetetrahydrofolate reductase -methylenetetrahydrofolate reductase	EC-1.5.1.20	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 16954 Tiso gene 14582	PWY-2201 1CMET2-PWY CODH-PWY PWY-3841
1.5.1.7-RXN		EC-1.5.1.7	Orthology	Pantograph	Orthology-athaliana	Tiso gene 1156	LYSINE-AMINOAD-PWY
1.5.1.8-RXN		EC-1.5.1.8	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation	Tiso gene 1156	LYSINE-DEG1-PWY
1.5.1.9-RXN	Saccharopine dehydrogenase	EC-1.5.1.9	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9366 Tiso gene 7038 Tiso gene 7039 Tiso gene 4160 Tiso gene 10095 Tiso gene 1156	LYSINE-DEG1-PWY
1.5.5.1-RXN		EC-1.5.5.1	Orthology Manual	Pantograph	Manual-primary network Orthology-esiliculosus	Tiso gene 18526
1.6.4.4-RXN	Nucleoredoxin ORF	EC-1.8.1.8	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 475 Tiso gene 15704
1.6.5.4-RXN		EC-1.6.5.4	Orthology	Pantograph	Orthology-athaliana	Tiso gene 2478	PWY-6370
1.8.1.4-RXN	E3 component of α-ketoacid dehydrogenase complexes Diaphorase	EC-1.8.1.4	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 9330
1.8.3.5-RXN		EC-1.8.3.5	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 17144
1.8.4.12-RXN	Peptide methionine-r-sulfoxide reductase ORF Methionine sulfoxide reductase with associated domain Methionine sulfoxide reductase b	EC-1.8.4.12	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 16975 Tiso gene 6049 Tiso gene 18058 Tiso gene 14455 Tiso gene 19578
1.8.4.14-RXN	Peptide methionine-r-sulfoxide reductase	EC-1.8.4.14	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 19578
1.8.4.8-RXN		EC-1.8.4.8	Orthology	Pantograph	Orthology-synechocystis Orthology-esiliculosus	Tiso gene 15770	SO4ASSIM-PWY
1.8.4.9-RXN		EC-1.8.4.9	Manual		Manual-primary network		SULFMETII-PWY
13-BETA-GLUCAN-SYNTHASE-RXN	-beta-glucan synthase component gls2 Callose synthase Callose Beta-glucan synthesis-associated	EC-2.4.1.34	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 7603 Tiso gene 5462 Tiso gene 7967 Tiso gene 7966 Tiso gene 3322 Tiso gene 5460	PWY-6773
14-LACTONASE-RXN	Gluconolactonase	EC-3.1.1.25	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 1948 Tiso gene 1947
1TRANSKETO-RXN	Transketolase	EC-2.2.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Orthology-athaliana Annotation-experimental annotation Orthology-synechocystis	Tiso gene 5008 Tiso gene 11559	P124-PWY CALVIN-PWY P21-PWY PWY-5723 PWY-1861 P185-PWY NONOXIPENT-PWY

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