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	Common name	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
3-HYDROXYBUTYRATE-DEHYDROGENASE-RXN		EC-1.1.1.30	Orthology	Pantograph	Orthology-creinhardtii	Tiso gene 7191 Tiso gene 12472	PWY66-367 PWY66-368
3-HYDROXYBUTYRYL-COA-DEHYDROGENASE-RXN		EC-1.1.1.157	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 14026 Tiso gene 14027
3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN	3-hydroxyisobutyrate mitochondrial 3-hydroxyisobutyrate dehydrogenase Uncharacterized oxidoreductase	EC-1.1.1.31	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus Annotation-experimental annotation	Tiso gene 19590 Tiso gene 5857 Tiso gene 19771 Tiso gene 7107 Tiso gene 19772 Tiso gene 19592	VALDEG-PWY
3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN	Enoyl- hydratase	EC-3.1.2.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-creinhardtii Annotation-experimental annotation	Tiso gene 2224	VALDEG-PWY
3-ISOPROPYLMALDEHYDROG-RXN	3-isopropylmalate dehydrogenase Β-isopropylmalic enzyme Threo-Ds-3-isopropylmalate dehydrogenase		Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-experimental annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 2920	LEUSYN-PWY PWY-6871
3-ISOPROPYLMALISOM-RXN	3-isopropylmalate dehydratase ORF (2R,3S)-3-isopropylmalate hydro-lyase Β-isopropylmalate dehydratase Α-isopropylmalate isomerase 3-isopropylmalate hydro-lyase		Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 12778	LEUSYN-PWY PWY-6871
3-OXOACYL-ACP-REDUCT-RXN	Polyketide synthase 3-oxoacyl-(acyl-carrier-protein)	EC-2.3.1.86 EC-2.3.1.85 EC-1.1.1.100	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 10876 Tiso gene 13394 Tiso gene 9885 Tiso gene 135 Tiso gene 13083 Tiso gene 136 Tiso gene 500	FASYN-ELONG-PWY
3-OXOACYL-ACP-SYNTH-BASE-RXN	3-oxoacyl-synthase Polyketide synthase	EC-2.3.1.86 EC-2.3.1.85 EC-2.3.1.41	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 19302 Tiso gene 136 Tiso gene 14485 Tiso gene 13394 Tiso gene 5939 Tiso gene 135 Tiso gene 10876 Tiso gene 500 Tiso gene 15991	PWY-5965 PWY-5966 FASYN-INITIAL-PWY PWY-7388
3-OXOACYL-ACP-SYNTH-RXN	Polyketide synthase 3-oxoacyl-synthase	EC-2.3.1.86 EC-2.3.1.85 EC-2.3.1.41	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 136 Tiso gene 15991 Tiso gene 14485 Tiso gene 135 Tiso gene 13394 Tiso gene 500 Tiso gene 5939 Tiso gene 10876 Tiso gene 19302	FASYN-ELONG-PWY
3-SULFINOALANINE-AMINOTRANSFERASE-RXN		EC-2.6.1	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 17718	CYSTEINE-DEG-PWY
3.1.1.64-RXN	All-trans-retinyl-palmitate hydrolase ORF Alpha beta hydrolase fold protein Alpha beta hydrolase Serine esterase Sialate o-acetylesterase-like protein Lysophospholipase Protein chloroplastic Para-nitrobenzyl esterase	EC-3.1.1.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 1538 Tiso gene 1537 Tiso gene 9429 Tiso gene 1922 Tiso gene 2556 Tiso gene 19778 Tiso gene 12686 Tiso gene 4606 Tiso gene 4650 Tiso gene 10066 Tiso gene 17029 Tiso gene 16518 Tiso gene 11351
3.1.26.4-RXN	Ribonuclease ORF	EC-3.1.26.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9453 Tiso gene 3410 Tiso gene 9459 Tiso gene 16584 Tiso gene 10743
3.1.26.5-RXN	Oxidoreductase ORF	EC-3.1.26.5	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 14345 Tiso gene 14344 Tiso gene 10972 Tiso gene 3898 Tiso gene 10971	PWY0-1479
3.1.27.1-RXN	Uncharacterized protein ORF	EC-3.1.27.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 11979 Tiso gene 13100 Tiso gene 8896
3.1.3.16-RXN	Formin domain containing protein Formin-like protein 14 Protein phosphatase 1 ORF Serine threonine-protein phosphatase Serine threonine protein phosphatase 2a Serine threonine-phosphatase Protein phosphatase Dual specificity phosphatase Protein phosphatase 2c	EC-3.1.3.16	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 452 Tiso gene 2190 Tiso gene 7036 Tiso gene 3751 Tiso gene 15176 Tiso gene 17314 Tiso gene 5305 Tiso gene 1395 Tiso gene 10912 Tiso gene 7035 Tiso gene 2578 Tiso gene 15559 Tiso gene 13371 Tiso gene 18472 Tiso gene 19603 Tiso gene 16524 Tiso gene 15788 Tiso gene 16525 Tiso gene 20309 Tiso gene 4137 Tiso gene 12379 Tiso gene 4164 Tiso gene 2034 Tiso gene 11870 Tiso gene 453 Tiso gene 18502 Tiso gene 12989 Tiso gene 1840
3.1.3.46-RXN		EC-3.1.3.46	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 15398 Tiso gene 2100 Tiso gene 893 Tiso gene 892	PWY66-423
3.1.3.57-RXN		EC-3.1.3.57	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation	Tiso gene 12601	PWY-6363
3.1.3.67-RXN		EC-3.1.3.67	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 19083	PWY-6368
3.1.3.74-RXN		EC-3.1.3.74	Orthology	Pantograph	Orthology-creinhardtii	Tiso gene 18054	PWY-7204
3.1.4.11-RXN	Phospholipase c beta 4 1-phosphatidylinositol- -bisphosphate phosphodiesterase gamma-2	EC-3.1.4.11	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 7561 Tiso gene 12020 Tiso gene 12019	PWY-6367 PWY-6351 PWY-7039 LIPASYN-PWY
3.1.4.17-RXN	Iesterase family member Amino acid transporter	EC-3.1.4.17	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9644 Tiso gene 1763 Tiso gene 12792
3.2.1.106-RXN	Mannosyl-oligosaccharide glucosidase	EC-3.2.1.106	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 12662
3.2.1.113-RXN	Probable alpha-mannosidase i mns5 Mannosyl-oligosaccharide -alpha-mannosidase mns2 Class member 1	EC-3.2.1.113	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 4788 Tiso gene 11681 Tiso gene 2719
3.2.1.21-RXN	Beta-glucosidase-like chloroplastic ORF Low quality protein: beta-glucosidase-like chloroplastic-like Beta glucosidase	EC-3.2.1.21	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 6187 Tiso gene 15066 Tiso gene 3467 Tiso gene 8669 Tiso gene 5836 Tiso gene 6188 Tiso gene 2843 Tiso gene 15067 Tiso gene 6497 Tiso gene 13305 Tiso gene 13306 Tiso gene 6007 Tiso gene 10001 Tiso gene 2344
3.2.1.23-RXN	Polyprotein Glycoside hydrolase	EC-3.2.1.23	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 1398 Tiso gene 17558 Tiso gene 12839
3.2.1.24-RXN		EC-3.2.1.24	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 6748
3.2.1.39-RXN		EC-3.2.1.39	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 2599 Tiso gene 8689 Tiso gene 16519
3.2.1.47-RXN		EC-3.2.1.47	Orthology	Pantograph	Orthology-athaliana	Tiso gene 3392
3.2.1.58-RXN	Probable glucan 1,3-beta-glucosidase A	EC-3.2.1.58	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 16125
3.2.1.84-RXN	Neutral alpha-glucosidase ab	EC-3.2.1.84	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 2588
3.2.2.17-RXN		EC-3.2.2.17	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 11329
3.4.11.18-RXN	Methionine aminopeptidase	EC-3.4.11.18	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 5715 Tiso gene 3182 Tiso gene 4247
3.4.11.2-RXN	Aminopeptidase n Membrane aminopeptidase i	EC-3.4.11.2	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 16906 Tiso gene 860
3.4.21.102-RXN		EC-3.4.21.102	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 14917
3.4.21.4-RXN	Trypsin family Trypsin	EC-3.4.21.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 2777 Tiso gene 1761 Tiso gene 4842 Tiso gene 13074 Tiso gene 12875 Tiso gene 17883 Tiso gene 13684 Tiso gene 1341 Tiso gene 20549 Tiso gene 8820 Tiso gene 4147 Tiso gene 19324 Tiso gene 1997
3.4.21.89-RXN		EC-3.4.21.89	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 14208
3.4.21.92-RXN	ATP-dependent Clp protease proteolytic subunit	EC-3.4.21.92	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 10324 Tiso gene 11705 Tiso gene 10005 Tiso gene 999
3.4.22.1-RXN		EC-3.4.22.1	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 15207
3.4.22.15-RXN		EC-3.4.22.15	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 12789 Tiso gene 12787
3.4.22.68-RXN		EC-3.4.22.68	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 2617
3.4.23.1-RXN		EC-3.4.23.1	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 1894 Tiso gene 12450
3.4.24.70-RXN		EC-3.4.24.70	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 4170
3.4.25.1-RXN	26S protease regulatory subunit 7 26S protease regulatory subunit 8 homolog B	EC-3.4.25.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 19087 Tiso gene 1855 Tiso gene 16496 Tiso gene 11443 Tiso gene 18135 Tiso gene 3310 Tiso gene 11901 Tiso gene 5953 Tiso gene 7332 Tiso gene 20415 Tiso gene 2549
3.5.1.98-RXN	Sir2-family protein hdac1 Histone deacetylase ORF Histone deacetylase 7a Histone deacetylase 1	EC-3.5.1.98	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 10459 Tiso gene 17880 Tiso gene 17340 Tiso gene 12946 Tiso gene 12131 Tiso gene 16490 Tiso gene 3315 Tiso gene 17377 Tiso gene 275 Tiso gene 18096 Tiso gene 727 Tiso gene 19850 Tiso gene 18920
3.5.2.17-RXN	5-hydroxyisourate hydrolase	EC-3.5.2.17	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-in-silico annotation	Tiso gene 13181	PWY-7394 PWY-5691
3.6.1.41-RXN	Metallophosphatase	EC-3.6.1.41	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-in-silico annotation	Tiso gene 6311 Tiso gene 19348 Tiso gene 19347
3.6.3.1-RXN	ORF Haloacid dehalogenaselike hydrolase family protein Atpase	EC-3.6.3.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 13202 Tiso gene 7790 Tiso gene 13203 Tiso gene 13177 Tiso gene 11648 Tiso gene 7789
3.6.3.50-RXN		EC-3.6.3.50	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 6012 Tiso gene 8153 Tiso gene 15988 Tiso gene 11192 Tiso gene 10760 Tiso gene 11155 Tiso gene 5307 Tiso gene 1145 Tiso gene 11754 Tiso gene 9460 Tiso gene 1366 Tiso gene 1790 Tiso gene 2798 Tiso gene 12185 Tiso gene 11648 Tiso gene 7873 Tiso gene 12618 Tiso gene 18105
3.6.4.4-RXN	Kinesin	EC-3.6.4.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9800 Tiso gene 16240 Tiso gene 18523 Tiso gene 12881 Tiso gene 15652 Tiso gene 14940 Tiso gene 1492 Tiso gene 5584 Tiso gene 2393 Tiso gene 10834 Tiso gene 10355 Tiso gene 10356 Tiso gene 646 Tiso gene 14941 Tiso gene 6071
3.6.4.9-RXN			Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 1384

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