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	Common name	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
1.2.1.25-RXN	3-methyl-2-oxobutanoate dehydrogenase	EC-1.2.1.25	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 11793 Tiso gene 3260	VALDEG-PWY
1.2.1.27-RXN	Methylmalonate-semialdehyde dehydrogenase	EC-1.2.1.27	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 11323	PWY-5642
1.2.1.31-RXN	Polyketide synthase ORF	EC-1.2.1.31	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6563 Tiso gene 16719 Tiso gene 5425 Tiso gene 5424 Tiso gene 6562	LYSINE-DEG1-PWY
1.2.1.65-RXN		EC-1.2.1.65	Annotation	Pathwaytools	Annotation-in-silico annotation		PWY-5427
1.2.4.4-RXN	3-methyl-2-oxobutanoate dehydrogenase 2-oxoisovalerate dehydrogenase alpha subunit mitochondrial	EC-1.2.4.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 18084 Tiso gene 11793 Tiso gene 3260	PWY-5046
1.21.3.1-RXN		EC-1.21.3.1	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 3330	PWY-5629
1.3.1.20-RXN	Dihydrodiol dehydrogenase	EC-1.3.1.20	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 10406
1.3.1.9-RXN		EC-1.3.1.9	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 10778
1.3.7.3-RXN		EC-1.3.7.3	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 17350	PWY-5915 PWY-7579
1.3.7.4-RXN		EC-1.3.7.4	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 17350	PWY-7170
1.3.99.23-RXN	Carotenoid isomerase Carotene isomerase Fad nad -binding oxidoreductase domain-containing protein Carotenoid isomerase-like protein All-trans- -dihydroretinol saturase ORF	EC-1.3.99.23	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 13369 Tiso gene 9534 Tiso gene 3092 Tiso gene 917 Tiso gene 13367 Tiso gene 16795 Tiso gene 16794
1.3.99.5-RXN	3-oxo-5-alpha-steroid 4-dehydrogenase	EC-1.3.1.22	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 14327
1.4.3.19-RXN		EC-1.4.3.19	Orthology	Pantograph	Orthology-synechocystis	Tiso gene 16652 Tiso gene 13537 Tiso gene 11756	PWY-7396
1.5.1.19-RXN		EC-1.5.1.19	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 8893
1.5.1.20-RXN	Methylenetetrahydrofolate reductase -methylenetetrahydrofolate reductase	EC-1.5.1.20	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 16954 Tiso gene 14582	PWY-2201 1CMET2-PWY CODH-PWY PWY-3841
1.5.1.7-RXN		EC-1.5.1.7	Orthology	Pantograph	Orthology-athaliana	Tiso gene 1156	LYSINE-AMINOAD-PWY
1.5.1.8-RXN		EC-1.5.1.8	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation	Tiso gene 1156	LYSINE-DEG1-PWY
1.5.1.9-RXN	Saccharopine dehydrogenase	EC-1.5.1.9	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 9366 Tiso gene 7038 Tiso gene 7039 Tiso gene 4160 Tiso gene 10095 Tiso gene 1156	LYSINE-DEG1-PWY
1.5.5.1-RXN		EC-1.5.5.1	Orthology Manual	Pantograph	Manual-primary network Orthology-esiliculosus	Tiso gene 18526
1.6.4.4-RXN	Nucleoredoxin ORF	EC-1.8.1.8	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 475 Tiso gene 15704
1.6.5.4-RXN		EC-1.6.5.4	Orthology	Pantograph	Orthology-athaliana	Tiso gene 2478	PWY-6370
1.8.1.4-RXN	E3 component of α-ketoacid dehydrogenase complexes Diaphorase	EC-1.8.1.4	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 9330
1.8.3.5-RXN		EC-1.8.3.5	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 17144
1.8.4.12-RXN	Peptide methionine-r-sulfoxide reductase ORF Methionine sulfoxide reductase with associated domain Methionine sulfoxide reductase b	EC-1.8.4.12	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 16975 Tiso gene 6049 Tiso gene 18058 Tiso gene 14455 Tiso gene 19578
1.8.4.14-RXN	Peptide methionine-r-sulfoxide reductase	EC-1.8.4.14	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 19578
1.8.4.8-RXN		EC-1.8.4.8	Orthology	Pantograph	Orthology-synechocystis Orthology-esiliculosus	Tiso gene 15770	SO4ASSIM-PWY
1.8.4.9-RXN		EC-1.8.4.9	Manual		Manual-primary network		SULFMETII-PWY
13-BETA-GLUCAN-SYNTHASE-RXN	-beta-glucan synthase component gls2 Callose synthase Callose Beta-glucan synthesis-associated	EC-2.4.1.34	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 7603 Tiso gene 5462 Tiso gene 7967 Tiso gene 7966 Tiso gene 3322 Tiso gene 5460	PWY-6773
14-LACTONASE-RXN	Gluconolactonase	EC-3.1.1.25	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 1948 Tiso gene 1947
1TRANSKETO-RXN	Transketolase	EC-2.2.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Orthology-athaliana Annotation-experimental annotation Orthology-synechocystis	Tiso gene 5008 Tiso gene 11559	P124-PWY CALVIN-PWY P21-PWY PWY-5723 PWY-1861 P185-PWY NONOXIPENT-PWY
2-AMINOADIPATE-AMINOTRANSFERASE-RXN		EC-2.6.1.39	Annotation	Pathwaytools	Annotation-in-silico annotation		PWY-3081 PWY-5283 LYSINE-AMINOAD-PWY LYSINE-DEG1-PWY PWY66-425
2-DEHYDROPANTOATE-REDUCT-RXN	2-dehydropantoate 2-reductase	EC-1.1.1.169	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-synechocystis	Tiso gene 16426 Tiso gene 10174 Tiso gene 12761 Tiso gene 10173 Tiso gene 12762 Tiso gene 9392	PANTO-PWY PWY-6654
2-HALOACID-DEHALOGENASE-RXN	Had family hydrolase	EC-3.8.1.10 EC-3.8.1.2	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 3200
2-ISOPROPYLMALATESYN-RXN	2-isopropylmalate synthase chloroplastic	EC-2.3.3.13	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 11453	LEUSYN-PWY PWY-6871
2-KETO-ADIPATE-DEHYDROG-RXN			Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation	Tiso gene 9330 Tiso gene 10209	PWY-5652 PWY66-425 LYSINE-DEG1-PWY
2-OCTAPRENYL-6-OHPHENOL-METHY-RXN	2-octaprenyl-6-hydroxyphenyl methylase 3-demethylubiquinone-9 3-methyltransferase	EC-2.1.1.222	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6943	PWY-6708
2-OCTAPRENYL-METHOXY-BENZOQ-METH-RXN		EC-2.1.1.201	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 19352	PWY-6708 PWY-5870
2.1.1.109-RXN	O-methyltransferase i	EC-2.1.1.109	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 20416	PWY-5956
2.1.1.113-RXN		EC-2.1.1.113	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 10259
2.1.1.127-RXN	Ribulose- bisphosphate carboxylase oxygenase large subunit n- chloropl	EC-2.1.1.127	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 6151
2.1.1.137-RXN	ORF	EC-2.1.1.137	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 16361	PWY-4202
2.1.1.138-RXN	ORF	EC-2.1.1.137	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 16361	PWY-4202
2.1.1.143-RXN	Sterol methyltransferase	EC-2.1.1.143	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 11850 Tiso gene 11849	PWY-2541
2.1.1.63-RXN	Heat shock 40 kda protein Domain-containing protein	EC-2.1.1.63	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 12990 Tiso gene 12732
2.1.1.77-RXN	ORF L-isoaspartyl proteincarboxylmethyltransferase	EC-2.1.1.77	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 16936 Tiso gene 12221 Tiso gene 16935 Tiso gene 6376
2.1.1.79-RXN		EC-2.1.1.79	Orthology	Pantograph	Orthology-esiliculosus	Tiso gene 7622	PWY0-541
2.3.1.118-RXN	Arylamine n-acetyltransferase	EC-2.3.1.118	Annotation	Pathwaytools	Annotation-in-silico annotation Annotation-experimental annotation	Tiso gene 9942
2.3.1.155-RXN		EC-2.3.1.155	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation		PWY-7654 PWY-7656
2.3.1.165-RXN	Polyketide synthase	EC-2.3.1.165	Annotation	Pathwaytools	Annotation-in-silico annotation	Tiso gene 136 Tiso gene 13394 Tiso gene 10876 Tiso gene 500 Tiso gene 135	PWY-7490
2.3.1.168-RXN	3-methyl-2-oxobutanoate dehydrogenase	EC-2.3.1.168	Annotation	Pathwaytools	Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 11793 Tiso gene 3260	PWY-5046

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