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	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
RXN-9896		Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 13940	PWY-6100
RXN0-1441	EC-3.6.1.53 EC-3.6.1.13	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 15496 Tiso gene 17630 Tiso gene 9180 Tiso gene 7189 Tiso gene 17632 Tiso gene 2747
RXN0-1461	EC-1.3.3.3	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 3671 Tiso gene 13364 Tiso gene 2246 Tiso gene 2247 Tiso gene 13365	PWY0-1415 PWY-7159 CHLOROPHYLL-SYN HEME-BIOSYNTHESIS-II
RXN0-1602	EC-3.6.1.66	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 18793
RXN0-1603	EC-3.6.1.66	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 18793
RXN0-276	EC-1.1.1	Orthology	Pantograph	Orthology-athaliana	Tiso gene 18459
RXN0-3542	EC-3.6.1	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 12899
RXN0-385	EC-3.6.1.9	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 18792 Tiso gene 18793
RXN0-5073	EC-3.6.1	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 12899
RXN0-5114	EC-3.1.3.3	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 16271 Tiso gene 6236	SERSYN-PWY
RXN0-5180	EC-2.5.1	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 18201 Tiso gene 10317 Tiso gene 2848 Tiso gene 8531 Tiso gene 11582
RXN0-5187	EC-3.1.3.102	Orthology	Pantograph	Orthology-athaliana	Tiso gene 17529
RXN0-5217	EC-2.5.1	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 17803	PWY0-1303
RXN0-5408	EC-3.1.3.25	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus Annotation-experimental annotation	Tiso gene 12601 Tiso gene 11614 Tiso gene 4855 Tiso gene 14713 Tiso gene 10754 Tiso gene 2527	PWY-4702
RXN0-5462	EC-3.6.5.1 EC-3.6.5.2 EC-3.6.5.3 EC-3.6.5.4 EC-3.6.5.5 EC-3.6.5.6 EC-3.6.1.15	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 13738 Tiso gene 9114 Tiso gene 4092 Tiso gene 7387 Tiso gene 15465 Tiso gene 826 Tiso gene 674 Tiso gene 8949 Tiso gene 11012 Tiso gene 9926 Tiso gene 16252 Tiso gene 38 Tiso gene 538 Tiso gene 12899 Tiso gene 9659 Tiso gene 4437 Tiso gene 2068 Tiso gene 9234 Tiso gene 9423 Tiso gene 14239 Tiso gene 2889 Tiso gene 17751 Tiso gene 1960 Tiso gene 8950 Tiso gene 8859 Tiso gene 7123 Tiso gene 17449 Tiso gene 873 Tiso gene 4330 Tiso gene 14226 Tiso gene 4155 Tiso gene 10282 Tiso gene 537 Tiso gene 6181 Tiso gene 250 Tiso gene 4194 Tiso gene 19350 Tiso gene 8860 Tiso gene 1610 Tiso gene 20236 Tiso gene 8461 Tiso gene 13264 Tiso gene 2604 Tiso gene 13325 Tiso gene 14227 Tiso gene 2897 Tiso gene 20327 Tiso gene 572 Tiso gene 9243 Tiso gene 15500 Tiso gene 13653 Tiso gene 8584 Tiso gene 10221 Tiso gene 3653 Tiso gene 2176 Tiso gene 6614 Tiso gene 546 Tiso gene 14474 Tiso gene 19098 Tiso gene 8601 Tiso gene 14586 Tiso gene 14646 Tiso gene 14816 Tiso gene 2631 Tiso gene 2448 Tiso gene 20353 Tiso gene 8763 Tiso gene 2924 Tiso gene 7734 Tiso gene 2447 Tiso gene 4436 Tiso gene 1291 Tiso gene 9004 Tiso gene 1541 Tiso gene 17616 Tiso gene 5525 Tiso gene 4026 Tiso gene 12149 Tiso gene 829 Tiso gene 5166 Tiso gene 13681 Tiso gene 7745 Tiso gene 11098 Tiso gene 1984 Tiso gene 1959 Tiso gene 195 Tiso gene 6180 Tiso gene 12148 Tiso gene 2450 Tiso gene 199 Tiso gene 15320 Tiso gene 5529 Tiso gene 1444 Tiso gene 9959 Tiso gene 2449 Tiso gene 2929 Tiso gene 4726 Tiso gene 4596 Tiso gene 8164 Tiso gene 4192 Tiso gene 623 Tiso gene 2451 Tiso gene 2452 Tiso gene 16478 Tiso gene 1611 Tiso gene 13268 Tiso gene 15043 Tiso gene 3287
RXN0-6382	EC-3.6.1.9	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 18793 Tiso gene 18792
RXN0-901	EC-1.17.1.4	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation	Tiso gene 11775	PWY-5497 SALVADEHYPOX-PWY P164-PWY PWY-6596 PWY-6607 PWY-6606 PWY-6999 PWY-6608 PWY-5695 PWY-6538
RXN1F-144	EC-2.5.1.99	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 15914
RXN1F-147	EC-5.5.1.18	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 8263 Tiso gene 1547 Tiso gene 6282 Tiso gene 11980 Tiso gene 4457 Tiso gene 3577	PWY-5946
RXN1F-148	EC-5.5.1.19	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 8263 Tiso gene 4457 Tiso gene 6282 Tiso gene 3577 Tiso gene 11980 Tiso gene 1547	PWY-5947
RXN1F-150	EC-5.5.1.19	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 4457 Tiso gene 3577 Tiso gene 6282 Tiso gene 8263 Tiso gene 1547 Tiso gene 11980	PWY-5943 PWY-7591
RXN1F-151	EC-5.5.1.19	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 1547 Tiso gene 4457 Tiso gene 3577 Tiso gene 8263 Tiso gene 6282 Tiso gene 11980	PWY-5943
RXN1F-162	EC-1.14.11	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 3330	PWY-5070
RXN1F-163	EC-1.14.11	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 3330	PWY-5070
RXN1F-165	EC-1.14.11	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 3330	PWY-5070
RXN1F-167	EC-1.14.11	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 3330	PWY-5035
RXN1F-168	EC-1.14.11.12	Orthology	Pantograph	Orthology-athaliana	Tiso gene 3330	PWY-5035
RXN1F-20	EC-6.6.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-athaliana Orthology-esiliculosus	Tiso gene 5993 Tiso gene 9870 Tiso gene 11960	PWY-5531 CHLOROPHYLL-SYN PWY-7159
RXN1F-93	EC-1.14.11.23	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 3330	PWY-3101 PWY-6787
RXN1K-87		Orthology	Pantograph	Orthology-athaliana	Tiso gene 19690
RXN3DJ-11230	EC-4.3.2	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 105	PWY3DJ-11470
RXN3O-1803	EC-2.3.1.86 EC-2.3.1.41	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 14485 Tiso gene 15991 Tiso gene 13394 Tiso gene 500 Tiso gene 136 Tiso gene 19302 Tiso gene 10876 Tiso gene 5939 Tiso gene 135	PWY3O-355
RXN3O-218	EC-1.14.19.20	Orthology	Pantograph	Orthology-athaliana	Tiso gene 5446	PWY-2541 PWY-6075
RXN490-3641	EC-1.14.11	Orthology Manual	Pantograph	Manual-primary network Orthology-creinhardtii Orthology-athaliana Orthology-esiliculosus	Tiso gene 18208 Tiso gene 19638 Tiso gene 15328 Tiso gene 9035 Tiso gene 2280 Tiso gene 292 Tiso gene 16842 Tiso gene 18145 Tiso gene 17919 Tiso gene 6296 Tiso gene 9636 Tiso gene 8652 Tiso gene 15594 Tiso gene 3021 Tiso gene 13008 Tiso gene 16122 Tiso gene 17823 Tiso gene 9165 Tiso gene 18689 Tiso gene 9455 Tiso gene 1468 Tiso gene 18933 Tiso gene 9227 Tiso gene 2158 Tiso gene 17593 Tiso gene 9873 Tiso gene 18235
RXN6666-4	EC-1.4.3.4	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 8756	PWY6666-2 PWY-7431
RXNQT-4142	EC-3.1.3.93	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 11614 Tiso gene 10754 Tiso gene 15599	PWY-882
S-ADENMETSYN-RXN	EC-2.5.1.6	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 13443	SAM-PWY PWY-5912 ETHYL-PWY METHIONINE-DEG1-PWY PWY-5041
SAMDECARB-RXN	EC-4.1.1.50	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 4269 Tiso gene 11030	BSUBPOLYAMSYN-PWY ARGSPECAT-PWY PWY-6834
SEDOBISALDOL-RXN	EC-4.1.2	Orthology Manual	Pantograph	Manual-primary network Orthology-athaliana Orthology-creinhardtii Orthology-synechocystis	Tiso gene 65 Tiso gene 14568 Tiso gene 9179 Tiso gene 12272	CALVIN-PWY PWY0-1517
SEDOHEPTULOSE-BISPHOSPHATASE-RXN	EC-3.1.3.37	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Manual-primary network Orthology-creinhardtii	Tiso gene 4905 Tiso gene 8226 Tiso gene 9435 Tiso gene 16502	CALVIN-PWY
SERINE-C-PALMITOYLTRANSFERASE-RXN	EC-2.3.1.50	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 10992	PWY-5129 PWY3DJ-12 SPHINGOLIPID-SYN-PWY
SERINE-O-ACETTRAN-RXN	EC-2.3.1.30	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 10634 Tiso gene 4492 Tiso gene 7066	CYSTSYN-PWY PWY-7274 PWY-6936
SPERMIDINESYN-RXN	EC-2.5.1.16	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 17803 Tiso gene 17081 Tiso gene 16718 Tiso gene 16717	BSUBPOLYAMSYN-PWY
SPHINGANINE-1-PHOSPHATE-ALDOLASE-RXN	EC-4.1.2.27	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 105	PWY-7119
STRICTOSIDINE-SYNTHASE-RXN	EC-4.3.3.2	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation	Tiso gene 8473 Tiso gene 8474	PWY-5290 PWY-6326
SUCCCOASYN-RXN	EC-6.2.1.5	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 11866 Tiso gene 15846	PWY-5913 P42-PWY PWY-7384 PWY-5392 P23-PWY PWY-6969 PWY-5537 PWY-6728 PWY-5538 PWY-5690 PWY66-398 TCA
SULFATE-ADENYLYLTRANS-RXN	EC-2.7.7.4	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus Orthology-synechocystis	Tiso gene 17879 Tiso gene 10254	DISSULFRED-PWY PWY-5340 PWY-5278 SULFMETII-PWY PWY-6683 P224-PWY
SULFITE-REDUCTASE-FERREDOXIN-RXN	EC-1.8.7.1	Orthology	Pantograph	Orthology-athaliana Orthology-synechocystis Orthology-esiliculosus	Tiso gene 10247	SULFMETII-PWY
SULFOCYS-RXN	EC-2.5.1.47	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 7852 Tiso gene 12184 Tiso gene 6110 Tiso gene 3732 Tiso gene 819 Tiso gene 17043 Tiso gene 2283
TCM3		Orthology	Pantograph	Orthology-athaliana	Tiso gene 7472

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