Tiso gene 432

Reaction RXN-14326

• direction:
  • LEFT-TO-RIGHT
• common name:
  • diphthine_synthase
• ec number:
  • EC-2.1.1.98
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 2-3-CARBOXY-3-AMINOPROPYL-L-HISTIDINE[c] + 3 S-ADENOSYLMETHIONINE[c] => 3 ADENOSYL-HOMO-CYS[c] + 3 PROTON[c] + 1 DIPHTINE[c]
• With common name(s):
  • 1 a 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2][c] + 3 S-adenosyl-L-methionine[c] => 3 S-adenosyl-L-homocysteine[c] + 3 H+[c] + 1 a diphthine-[translation elongation factor 2][c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_15743
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • pantograph-esiliculosus

Pathways

• PWY-6482, diphthamide biosynthesis (archaea): PWY-6482
  • 2 reactions found over 3 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • esiliculosus
• annotation:
  • pathwaytools:
    • in-silico_annotation

External links

• LIGAND-RXN:
  • R10306