Tiso gene 5611

Reaction RXN66-11

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 24,25-dihydrolanosterol 14-hydroxylase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CPD-8606[c] + 1 NADPH[c] + 1 OXYGEN-MOLECULE[c] + 1 PROTON[c] => 1 WATER[c] + 1 CPD-8607[c] + 1 NADP[c]
• With common name(s):
  • 1 24,25-dihydrolanosterol[c] + 1 NADPH[c] + 1 oxygen[c] + 1 H+[c] => 1 H2O[c] + 1 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol[c] + 1 NADP+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_8263
  • pantograph-esiliculosus

Pathways

• PWY66-3, cholesterol biosynthesis II (via 24,25-dihydrolanosterol): PWY66-3
  • 8 reactions found over 22 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • esiliculosus