CPD-8549

Reaction CORTISONE-ALPHA-REDUCTASE-RXN

• direction:
  • REVERSIBLE
• common name:
  • cortisone α-reductase
  • 3-oxo-5-alpha-steroid_4-dehydrogenase
• ec number:
  • EC-1.3.1.22
• Synonym(s):
  • cortisone Δ4-5α-reductase
  • microsomal steroid reductase (5α)
  • Δ4-3-ketosteroid reductase (5α)
  • Δ4-3-oxosteroid-5α-reductase
  • NADPH:Δ4-3-oxosteroid-5α-oxidoreductase
  • Δ4-5α-reductase

Reaction Formula

• With identifiers:
  • 1 CPD-286[c] + 1 NADP[c] <=> 1 NADPH[c] + 1 CORTISONE[c] + 1 PROTON[c]
• With common name(s):
  • 1 4,5α-dihydrocortisone[c] + 1 NADP+[c] <=> 1 NADPH[c] + 1 cortisone[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_14327
  • IN-SILICO_ANNOTATION
    • AUTOMATED-NAME-MATCH

Reconstruction information

• annotation:
  • pathwaytools:
    • in-silico_annotation

External links

• RHEA:
  • 17981
• LIGAND-RXN:
  • R02892