TROPINE-DEHYDROGENASE-RXN

Reaction 1.1.1.39-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • mitochondrial_malic_enzyme
  • ORF
• ec number:
  • EC-1.1.1.38
  • EC-1.1.1.39
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 MAL[c] + 1 NAD[c] => 1 CARBON-DIOXIDE[c] + 1 PYRUVATE[c] + 1 NADH[c]
• With common name(s):
  • 1 (S)-malate[c] + 1 NAD+[c] => 1 CO2[c] + 1 pyruvate[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_12896
  • pantograph-esiliculosus
• Tiso_gene_6675
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • EXPERIMENTAL_ANNOTATION
    • EC-NUMBER
• Tiso_gene_12200
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • EXPERIMENTAL_ANNOTATION
    • EC-NUMBER
  • pantograph-esiliculosus

Pathways

• PWY-3641, L-carnitine degradation III: PWY-3641
  • 2 reactions found over 3 reactions in the full pathway
• GLUCONEO-PWY, gluconeogenesis I: GLUCONEO-PWY
  • 13 reactions found over 13 reactions in the full pathway
• PWY-7384, anaerobic energy metabolism (invertebrates, mitochondrial): PWY-7384
  • 7 reactions found over 12 reactions in the full pathway
• PWY-7686, L-malate degradation II: PWY-7686
  • 1 reactions found over 1 reactions in the full pathway
• PWY-7115, C4 photosynthetic carbon assimilation cycle, NAD-ME type: PWY-7115
  • 7 reactions found over 9 reactions in the full pathway
• PWY-7118, chitin degradation to ethanol: PWY-7118
  • 4 reactions found over 6 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 12653
• LIGAND-RXN:
  • R00214
• UNIPROT:
  • Q48662
  • Q9PN12
  • O59029
  • P16468
  • Q9CGB2
  • P26616
  • Q9JVE6
  • P37224
  • P37225
  • P37221
  • Q7M1T9
  • Q9M162