TRANS-RXN-249

Reaction RXN-12610

• direction:
  • LEFT-TO-RIGHT
• common name:
  • ORF
  • thiamine_monophosphate_synthase
• ec number:
  • EC-2.5.1.3
• Synonym(s):

Reaction Formula

• With identifiers:
  • 2 PROTON[c] + 1 AMINO-HYDROXYMETHYL-METHYLPYRIMIDINE-PP[c] + 1 CPD-13576[c] => 1 PPI[c] + 1 CARBON-DIOXIDE[c] + 1 THIAMINE-P[c]
• With common name(s):
  • 2 H+[c] + 1 4-amino-2-methyl-5-(diphosphomethyl)pyrimidine[c] + 1 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate[c] => 1 diphosphate[c] + 1 CO2[c] + 1 thiamine phosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_2159
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_10320
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_2160
  • IN-SILICO_ANNOTATION
    • EC-NUMBER

Pathways

• PWY-6907, thiamine diphosphate biosynthesis III (Staphylococcus): PWY-6907
  • 3 reactions found over 3 reactions in the full pathway
• PWY-6893, thiamine diphosphate biosynthesis II (Bacillus): PWY-6893
  • 1 reactions found over 2 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools