CPD-15382

Reaction 3.1.4.11-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • phospholipase_c_beta_4
  • 1-phosphatidylinositol-_-bisphosphate_phosphodiesterase_gamma-2
• ec number:
  • EC-3.1.4.11
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 WATER[c] + 1 PHOSPHATIDYL-MYO-INOSITOL-45-BISPHOSPHA[c] => 1 INOSITOL-1-4-5-TRISPHOSPHATE[c] + 1 PROTON[c] + 1 DIACYLGLYCEROL[c]
• With common name(s):
  • 1 H2O[c] + 1 a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate[c] => 1 D-myo-inositol (1,4,5)-trisphosphate[c] + 1 H+[c] + 1 a 1,2-diacyl-sn-glycerol[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_12019
  • pantograph-esiliculosus
• Tiso_gene_12020
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • pantograph-esiliculosus
• Tiso_gene_7561
  • IN-SILICO_ANNOTATION
    • EC-NUMBER

Pathways

• PWY-6367, D-myo-inositol-5-phosphate metabolism: PWY-6367
  • 2 reactions found over 4 reactions in the full pathway
• PWY-6351, D-myo-inositol (1,4,5)-trisphosphate biosynthesis: PWY-6351
  • 5 reactions found over 5 reactions in the full pathway
• PWY-7039, phosphatidate metabolism, as a signaling molecule: PWY-7039
  • 2 reactions found over 5 reactions in the full pathway
• LIPASYN-PWY, phospholipases: LIPASYN-PWY
  • 2 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools

External links

• LIGAND-RXN:
  • R03435
• UNIPROT:
  • P10687
  • P10894
  • P10686
  • P24135
  • P19174
  • Q00722
  • Q02158
  • P32383
  • Q9TS13
  • Q24284
  • P51178
  • P10688
  • P10895
  • Q60450
  • P08487
  • Q9STZ3
  • P40977
  • Q21754