LEUKOTRIENE-A4-HYDROLASE-RXN

Reaction RXN-9952

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 3-hydroxyisobutyrate_mitochondrial
  • 6-phosphogluconate_decarboxylating
  • ORF
• ec number:
  • EC-1.1.1.44
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CPD-2961[c] + 1 NADP[c] => 1 RIBULOSE-5P[c] + 1 NADPH[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 D-gluconate 6-phosphate[c] + 1 NADP+[c] => 1 D-ribulose 5-phosphate[c] + 1 NADPH[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_91
  • pantograph-esiliculosus
• Tiso_gene_7157
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • pantograph-esiliculosus
• Tiso_gene_19590
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_20238
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • pantograph-esiliculosus
• Tiso_gene_777
  • pantograph-esiliculosus

Pathways

• OXIDATIVEPENT-PWY, pentose phosphate pathway (oxidative branch) I: OXIDATIVEPENT-PWY
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: manual
  • Source: manual-primary_network
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 10116
• LIGAND-RXN:
  • R01528