RXN-9653

Reaction PYRIMSYN3-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • phosphomethylpyrimidine_kinase
  • thiamine_monophosphate_synthase
• ec number:
  • EC-2.7.4.7
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 ATP[c] + 1 AMINO-HYDROXYMETHYL-METHYL-PYR-P[c] => 1 ADP[c] + 1 AMINO-HYDROXYMETHYL-METHYLPYRIMIDINE-PP[c]
• With common name(s):
  • 1 ATP[c] + 1 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine[c] => 1 ADP[c] + 1 4-amino-2-methyl-5-(diphosphomethyl)pyrimidine[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_2159
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_2160
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • pantograph-athaliana
  • pantograph-esiliculosus
• Tiso_gene_16224
  • IN-SILICO_ANNOTATION
    • AUTOMATED-NAME-MATCH
• Tiso_gene_17192
  • IN-SILICO_ANNOTATION
    • AUTOMATED-NAME-MATCH

Pathways

• PWY-6910, hydroxymethylpyrimidine salvage: PWY-6910
  • 1 reactions found over 2 reactions in the full pathway
• PWY-7282, 4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis (yeast): PWY-7282
  • 6 reactions found over 9 reactions in the full pathway
• PWY-6890, 4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis: PWY-6890
  • 1 reactions found over 2 reactions in the full pathway
• PWY-7356, thiamine salvage IV (yeast): PWY-7356
  • 5 reactions found over 7 reactions in the full pathway
• PWY-7357, thiamine formation from pyrithiamine and oxythiamine (yeast): PWY-7357
  • 3 reactions found over 6 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-athaliana
    • Tool: pantograph
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 19893
• LIGAND-RXN:
  • R04509
• UNIPROT:
  • Q9JTE1
  • Q9PNL2
  • Q9CI79
  • Q9CG47