CPD-17319

Reaction RXN-11680

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Delta-6 fatty acid desaturase
• ec number:
  • EC-1.14.19.47
• Synonym(s):

Reaction Formula

• With identifiers:
  • 2 PROTON[c] + 1 OXYGEN-MOLECULE[c] + 2 FERROCYTOCHROME-B5[c] + 1 Linoleoyl-groups[c] => 2 FERRICYTOCHROME-B5[c] + 2 WATER[c] + 1 Gamma-linolenoyl-groups[c]
• With common name(s):
  • 2 H+[c] + 1 oxygen[c] + 2 a ferrocytochrome b5[c] + 1 a [glycerolipid]-linoleate[c] => 2 a ferricytochrome b5[c] + 2 H2O[c] + 1 a [glycerolipid]-γ-linolenate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_9580
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_8027
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_18205
  • Source: annotation-in-silico_annotation
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: Tiso_gene_18056
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_7427
  • Source: orthology-esiliculosus

Pathways

• PWY-5353, arachidonate biosynthesis I (6-desaturase, lower eukaryotes): PWY-5353
  • 3 reactions found over 8 reactions in the full pathway
• PWY-6603, dicranin biosynthesis: PWY-6603
  • 1 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• LIGAND-RXN:
  • R07063