3.1.3.57-RXN

Reaction RXN-9535

• direction:
  • LEFT-TO-RIGHT
• common name:
  • polyketide_synthase
  • 3-oxoacyl-synthase
• ec number:
  • EC-2.3.1.86
  • EC-2.3.1.85
  • EC-2.3.1.41
• Synonym(s):
  • β-ketoacyl-ACP synthase I
  • β-ketoacyl-acyl carrier protein synthetase
  • β-ketoacyl-[acyl carrier protein] synthase
  • condensing enzyme
  • β-ketoacyl acyl carrier protein synthase
  • 3-oxoacyl-[acyl-carrier-protein] synthase
  • acyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)

Reaction Formula

• With identifiers:
  • 1 Dodecanoyl-ACPs[c] + 1 MALONYL-ACP[c] + 1 PROTON[c] => 1 ACP[c] + 1 3-oxo-myristoyl-ACPs[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 a dodecanoyl-[acp][c] + 1 a malonyl-[acp][c] + 1 H+[c] => 1 a holo-[acyl-carrier protein][c] + 1 a 3-oxo-myristoyl-[acp][c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Tiso_gene_14485
  • pantograph-synechocystis
  • pantograph-esiliculosus
• Tiso_gene_136
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_500
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_135
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_13394
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
• Tiso_gene_15991
  • pantograph-athaliana
  • pantograph-athaliana
  • pantograph-esiliculosus
• Tiso_gene_19302
  • pantograph-synechocystis
  • pantograph-esiliculosus
• Tiso_gene_5939
  • IN-SILICO_ANNOTATION
    • EC-NUMBER
  • EXPERIMENTAL_ANNOTATION
    • EC-NUMBER
• Tiso_gene_10876
  • IN-SILICO_ANNOTATION
    • EC-NUMBER

Pathways

• PWY-5971, palmitate biosynthesis II (bacteria and plants): PWY-5971
  • 31 reactions found over 31 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • synechocystis
    • esiliculosus
    • athaliana
• manual:
  • primary_network
• annotation:
  • pathwaytools:
    • experimental_annotation
    • in-silico_annotation

External links

• "β-ketoacyl-[acyl carrier protein] synthase" cannot be used as a page name in this wiki.
• "3-oxoacyl-[acyl-carrier-protein] synthase" cannot be used as a page name in this wiki.
• "acyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)" cannot be used as a page name in this wiki.