PWY-5835

Reaction FUMARYLACETOACETASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • fumarylacetoacetate_hydrolase
  • protein_fah-1
• ec number:
  • EC-3.7.1.2
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 4-FUMARYL-ACETOACETATE[c] + 1 WATER[c] => 1 FUM[c] + 1 3-KETOBUTYRATE[c] + 1 PROTON[c]
• With common name(s):
  • 1 4-fumaryl-acetoacetate[c] + 1 H2O[c] => 1 fumarate[c] + 1 acetoacetate[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_5675
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-athaliana
• Gene: Tiso_gene_2213
  • Source: annotation-in-silico_annotation
    • Assignment: AUTOMATED-NAME-MATCH

Pathways

• TYRFUMCAT-PWY, L-tyrosine degradation I: TYRFUMCAT-PWY
  • 4 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-athaliana
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 10244
• LIGAND-RXN:
  • R01364
• UNIPROT:
  • P16930
  • P35505
  • P25093