CPD-11518

Reaction GLYOXII-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • hydroxyacylglutathione_hydrolase
  • hydroxyacyl_glutathione_hydrolase
• ec number:
  • EC-3.1.2.6
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 S-LACTOYL-GLUTATHIONE[c] + 1 WATER[c] => 1 PROTON[c] + 1 GLUTATHIONE[c] + 1 D-LACTATE[c]
• With common name(s):
  • 1 (R)-S-lactoylglutathione[c] + 1 H2O[c] => 1 H+[c] + 1 glutathione[c] + 1 (R)-lactate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_10895
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-synechocystis
  • Source: orthology-esiliculosus
  • Source: orthology-creinhardtii
• Gene: Tiso_gene_5281
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_19886
  • Source: annotation-in-silico_annotation
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: Tiso_gene_12304
  • Source: orthology-synechocystis
• Gene: Tiso_gene_10894
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER

Pathways

• PWY-5386, methylglyoxal degradation I: PWY-5386
  • 2 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-creinhardtii
    • Tool: pantograph
  • Source: orthology-synechocystis
    • Tool: pantograph
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 25245
• LIGAND-RXN:
  • R01736
• UNIPROT:
  • Q9UZT9
  • P0AC84
  • Q9JWC6
  • O35952