CPD-4568

Reaction ACETOLACTSYN-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Acetolactate synthase catalytic subunit, mitochondrial
• ec number:
  • EC-2.2.1.6
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PROTON[c] + 2 PYRUVATE[c] => 1 2-ACETO-LACTATE[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 H+[c] + 2 pyruvate[c] => 1 (S)-2-acetolactate[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_11362
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER

Pathways

• VALSYN-PWY, L-valine biosynthesis: VALSYN-PWY
  • 4 reactions found over 4 reactions in the full pathway
• PWY-7111, pyruvate fermentation to isobutanol (engineered): PWY-7111
  • 4 reactions found over 5 reactions in the full pathway
• PWY-6389, (S)-acetoin biosynthesis: PWY-6389
  • 2 reactions found over 3 reactions in the full pathway
• PWY-5938, (R)-acetoin biosynthesis I: PWY-5938
  • 2 reactions found over 3 reactions in the full pathway
• PWY-5939, (R)-acetoin biosynthesis II: PWY-5939
  • 1 reactions found over 2 reactions in the full pathway

Reconstruction information

• Category: manual
  • Source: manual-primary_network
• Category: annotation
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 20504
  • 25249
• LIGAND-RXN:
  • R00226
• UNIPROT:
  • Q59950
  • P42463
  • Q8XAV3
  • P27868
  • P45260
  • Q57625
  • P37251
  • P45261
  • O27493
  • O66759
  • Q9PHU2
  • O05031
  • Q57725
  • Q9PHU1
  • Q9JTI1
  • Q58077
  • O28554
  • O53554
  • Q04789
  • Q9JRF4
  • Q59272
  • P27696
  • Q59498
  • Q9RFQ7
  • Q05767
  • P40811
  • P21622
  • P27818
  • Q41768
  • Q41769
  • P69684
  • P27819
  • Q9R586
  • Q02137
  • Q02140
  • P36620
  • Q42767
  • Q42768
  • Q49865
  • O22547
  • O49229
  • O22578
  • O49210
  • Q60021
  • P07342
  • P00892
  • P08142
  • P0ADF8
  • P00894
  • P00893
  • P17597
  • P09342
  • P09114
  • P14874