RXN-17857

Reaction RXN-9653

• direction:
  • LEFT-TO-RIGHT
• common name:
  • polyketide_synthase
  • 3-oxoacyl-synthase
• ec number:
  • EC-2.3.1.86
  • EC-2.3.1.85
  • EC-2.3.1.41
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 MALONYL-COA[c] + 1 PROTON[c] + 1 Dodecanoyl-ACPs[c] => 1 3-oxo-myristoyl-ACPs[c] + 1 CO-A[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 malonyl-CoA[c] + 1 H+[c] + 1 a dodecanoyl-[acp][c] => 1 a 3-oxo-myristoyl-[acp][c] + 1 coenzyme A[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_13394
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_10876
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_500
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_135
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_5939
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_15991
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_19302
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_14485
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_136
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER

Pathways

• PWY-5994, palmitate biosynthesis I (animals and fungi): PWY-5994
  • 31 reactions found over 31 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools