Gap-filling

	COMMON NAME	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Reconstruction comment	Gene associated	In pathway
1.1.1.8-RXN		EC-1.1.1.8	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-synechocystis Manual-primary network Orthology-creinhardtii		Tiso gene 13013 Tiso gene 15777 Tiso gene 6069 Tiso gene 2810 Tiso gene 2811 Tiso gene 3718	PWY-6118 PWY-7385 PWY-7411
1.14.19.1-RXN		EC-1.14.19.1	Orthology	Pantograph	Orthology-creinhardtii Orthology-esiliculosus		Tiso gene 1497 Tiso gene 9580 Tiso gene 8027 Tiso gene 18056 Tiso gene 19322 Tiso gene 7427 Tiso gene 19215	PWY-5996
2-ISOPROPYLMALATESYN-RXN		EC-2.3.3.13	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii		Tiso gene 11453	LEUSYN-PWY PWY-6871
2.4.1.123-RXN		EC-2.4.1.123	Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 18913	PWY-6524 PWY-6525 PWY-5337
2.4.1.67-RXN		EC-2.4.1.67	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus		Tiso gene 8673 Tiso gene 16101	PWY-5337
2.4.2.12-RXN		EC-2.4.2.12	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-in-silico annotation		Tiso gene 8411 Tiso gene 8186 Tiso gene 8410	NAD-BIOSYNTHESIS-III
2.5.1.19-RXN		EC-2.5.1.19	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Manual-primary network Annotation-in-silico annotation Orthology-athaliana		Tiso gene 5752 Tiso gene 5753	PWY-6163
2.7.1.121-RXN		EC-2.7.1.121	Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 14441	GLYCEROLMETAB-PWY
2.7.1.148-RXN		EC-2.7.1.148	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii		Tiso gene 13463	NONMEVIPP-PWY PWY-7560
2.7.7.14-RXN		EC-2.7.7.14	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus		Tiso gene 18070	PWY-7782 PWY4FS-6
2.7.7.60-RXN		EC-2.7.7.60	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-synechocystis Manual-primary network Orthology-creinhardtii		Tiso gene 17568	NONMEVIPP-PWY PWY-7560
2KETO-3METHYLVALERATE-RXN		EC-1.2.1	Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 3260 Tiso gene 18084 Tiso gene 11793	PWY-5108 ILEUDEG-PWY
2PGADEHYDRAT-RXN		EC-4.2.1.11	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii		Tiso gene 5619 Tiso gene 13317 Tiso gene 14718 Tiso gene 8720	PWY-1042 P341-PWY PWY-2221 PWY-7124 PWY-1622 GLUCONEO-PWY GLYCOLYSIS NPGLUCAT-PWY ANAGLYCOLYSIS-PWY PWY-7218 PWY-6901 P124-PWY PWY-6886 PWY-5723 PWY-6142 P122-PWY PWY66-399 PWY-5484 PWY-7003
2TRANSKETO-RXN		EC-2.2.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Manual-primary network		Tiso gene 11559 Tiso gene 5008	PWY-6901 CALVIN-PWY P21-PWY PWY-5723 PWY-1861 P185-PWY NONOXIPENT-PWY
3-DEHYDROQUINATE-SYNTHASE-RXN		EC-4.2.3.4	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii		Tiso gene 5753 Tiso gene 3446 Tiso gene 3445 Tiso gene 3974 Tiso gene 5752 Tiso gene 3447	PWY-6164
3-DEHYDROSPHINGANINE-REDUCTASE-RXN		EC-1.1.1.102	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-in-silico annotation		Tiso gene 18518	PWY-5129 PWY3DJ-12 SPHINGOLIPID-SYN-PWY
3-HYDROXYBUTYRATE-DEHYDROGENASE-RXN		EC-1.1.1.30	Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 7191 Tiso gene 12472	PWY66-367 PWY66-368
3-HYDROXYBUTYRYL-COA-DEHYDROGENASE-RXN		EC-1.1.1.157	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus		Tiso gene 14026 Tiso gene 14027
3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN		EC-1.1.1.31	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus Annotation-experimental annotation		Tiso gene 19590 Tiso gene 5857 Tiso gene 19771 Tiso gene 7107 Tiso gene 19772 Tiso gene 19592	VALDEG-PWY
3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN		EC-3.1.2.4	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-creinhardtii Annotation-experimental annotation		Tiso gene 2224	VALDEG-PWY
3.1.3.46-RXN		EC-3.1.3.46	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-experimental annotation Annotation-in-silico annotation		Tiso gene 15398 Tiso gene 2100 Tiso gene 893 Tiso gene 892	PWY66-423
3.1.3.74-RXN		EC-3.1.3.74	Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 18054	PWY-7204
3.5.2.17-RXN		EC-3.5.2.17	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-in-silico annotation		Tiso gene 13181	PWY-7394 PWY-5691
3.6.1.41-RXN		EC-3.6.1.41	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Annotation-in-silico annotation		Tiso gene 6311 Tiso gene 19348 Tiso gene 19347
325-BISPHOSPHATE-NUCLEOTIDASE-RXN		EC-3.1.3.7	Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 12601
34HPPYRI			Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 5011
35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN		EC-3.1.4.35	Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 9644 Tiso gene 13785 Tiso gene 12792
3PG pi thr			Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 5890 Tiso gene 6426 Tiso gene 17661
3PGAREARR-RXN		EC-5.4.2.12	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii		Tiso gene 16271 Tiso gene 5468 Tiso gene 14530 Tiso gene 7201 Tiso gene 20311 Tiso gene 2365 Tiso gene 10516 Tiso gene 16754 Tiso gene 9922 Tiso gene 2667 Tiso gene 15391 Tiso gene 2841 Tiso gene 15048 Tiso gene 14212 Tiso gene 9923 Tiso gene 14664	PWY-1042 P341-PWY PWY-2221 GLUCONEO-PWY GLYCOLYSIS PWY-6901 PWY-7218 P124-PWY PWY-6886 PWY-5723 PWY-6142 PWY-5484 PWY-7124 PWY-7003
4.1.99.4-RXN		EC-3.5.99.7	Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 11198
4.3.1.17-RXN		EC-4.3.1.17	Orthology Manual	Pantograph	Manual-primary network Orthology-creinhardtii Orthology-synechocystis		Tiso gene 12535
4.4.1.14-RXN		EC-4.4.1.14	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus		Tiso gene 8455	ETHYL-PWY PWY-7270
5-OXOPROLINASE-ATP-HYDROLYSING-RXN		EC-3.5.2.9	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus		Tiso gene 3358 Tiso gene 3359	PWY-4041
5.1.1.18-RXN		EC-5.1.1.18	Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 17207	PWY-6455 PWY-6196
5FLURAt			Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 6578 Tiso gene 18556 Tiso gene 18433
5FTHFt			Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 19115
5FTHFtm			Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 19115
6-PHOSPHOFRUCTO-2-KINASE-RXN		EC-2.7.1.105	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation		Tiso gene 2100 Tiso gene 892 Tiso gene 804 Tiso gene 893 Tiso gene 15398	PWY66-423
6MPURt			Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 18556 Tiso gene 6578 Tiso gene 18433
6PFRUCTPHOS-RXN		EC-2.7.1.11	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Manual-primary network Orthology-creinhardtii		Tiso gene 5733 Tiso gene 596	PWY-1042 GLYCOLYSIS PWY-7385 PWY-1861 ANAGLYCOLYSIS-PWY PWY-5484
6PGLUCONDEHYDROG-RXN		EC-1.1.1.351	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-synechocystis Orthology-esiliculosus		Tiso gene 20238 Tiso gene 91 Tiso gene 7157	P122-PWY
6PGLUCONOLACT-RXN		EC-3.1.1.31	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Manual-primary network Orthology-creinhardtii		Tiso gene 10799 Tiso gene 5901 Tiso gene 15950 Tiso gene 8585 Tiso gene 20412	P122-PWY RUMP-PWY OXIDATIVEPENT-PWY GLYCOLYSIS-E-D
AAL fum			Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 6720
AASP			Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 17878
ABor			Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 3513
ACACT			Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 15327
ACACT4			Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 16181
ACACT6			Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 16181
ACACT7			Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 16181
ACACT7m			Orthology	Pantograph	Orthology-creinhardtii		Tiso gene 16181
... further results