1.5.1.20-RXN

Reaction 1.5.1.20-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • methylenetetrahydrofolate_reductase
  • -methylenetetrahydrofolate_reductase
• ec number:
  • EC-1.5.1.20
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NADH[c] + 1 METHYLENE-THF-GLU-N[c] + 1 PROTON[c] => 1 5-METHYL-THF-GLU-N[c] + 1 NAD[c]
• With common name(s):
  • 1 NADH[c] + 1 a 5,10-methylene-tetrahydrofolate[c] + 1 H+[c] => 1 an N5-methyl-tetrahydrofolate[c] + 1 NAD+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_14582
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_16954
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER

Pathways

• PWY-2201, folate transformations I: PWY-2201
  • 7 reactions found over 12 reactions in the full pathway
• 1CMET2-PWY, N10-formyl-tetrahydrofolate biosynthesis: 1CMET2-PWY
  • 7 reactions found over 9 reactions in the full pathway
• CODH-PWY, reductive acetyl coenzyme A pathway I (homoacetogenic bacteria): CODH-PWY
  • 5 reactions found over 9 reactions in the full pathway
• PWY-3841, folate transformations II: PWY-3841
  • 9 reactions found over 11 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: manual
  • Source: manual-primary_network
• Category: annotation
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• LIGAND-RXN:
  • R07168
• UNIPROT:
  • Q9PN93
  • Q9JUT7
  • P45208
  • P0AEZ1
  • P11003
  • P46151
  • P53128