RXN-15212

Reaction RXN-15212

• direction:
  • LEFT-TO-RIGHT
• common name:
  • sphingomyelinase
• ec number:
  • EC-3.1.4.12
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 N-acyl-sphingosylphosphorylcholine[c] + 1 WATER[c] => 1 N-Acylsphingosine[c] + 1 PROTON[c] + 1 PHOSPHORYL-CHOLINE[c]
• With common name(s):
  • 1 an N-acyl-sphingosylphosphorylcholine[c] + 1 H2O[c] => 1 a sphingosine ceramide[c] + 1 H+[c] + 1 phosphocholine[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_12644
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER

Pathways

• PWY-7277, sphingolipid biosynthesis (mammals): PWY-7277
  • 5 reactions found over 7 reactions in the full pathway
• PWY3DJ-11281, sphingomyelin metabolism: PWY3DJ-11281
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools