1-PHOSPHATIDYLINOSITOL-KINASE-RXN

Reaction 1-PHOSPHATIDYLINOSITOL-KINASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • phosphatidylinositol-4-kinase
  • phosphatidylinositol_kinase
  • phosphatidylinositol_4-kinase_beta
  • ORF
• ec number:
  • EC-2.7.1.67
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 L-1-phosphatidyl-inositols[c] + 1 ATP[c] => 1 PROTON[c] + 1 CPD-1108[c] + 1 ADP[c]
• With common name(s):
  • 1 an L-1-phosphatidyl-inositol[c] + 1 ATP[c] => 1 H+[c] + 1 a 1-phosphatidyl-1D-myo-inositol 4-phosphate[c] + 1 ADP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_18530
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_12389
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_2572
  • Source: annotation-in-silico_annotation
    • Assignment: AUTOMATED-NAME-MATCH
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_18529
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_17239
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_17238
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_17240
  • Source: orthology-esiliculosus

Pathways

• PWY-6352, 3-phosphoinositide biosynthesis: PWY-6352
  • 3 reactions found over 8 reactions in the full pathway
• PWY-6351, D-myo-inositol (1,4,5)-trisphosphate biosynthesis: PWY-6351
  • 5 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 19877
• LIGAND-RXN:
  • R03361
• UNIPROT:
  • P18688
  • P12798
  • P39104
  • P42356
  • Q9UBF8
  • P37297
  • Q28925
  • O81281
  • O81129
  • Q9ZPE1