KYNURENINE-3-MONOOXYGENASE-RXN

Reaction KYNURENINE-3-MONOOXYGENASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • kynurenine_3-monooxygenase
• ec number:
  • EC-1.14.13.9
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 OXYGEN-MOLECULE[c] + 1 NADPH[c] + 1 PROTON[c] + 1 CPD-14736[c] => 1 3-HYDROXY-L-KYNURENINE[c] + 1 WATER[c] + 1 NADP[c]
• With common name(s):
  • 1 oxygen[c] + 1 NADPH[c] + 1 H+[c] + 1 L-kynurenine[c] => 1 3-hydroxy-L-kynurenine[c] + 1 H2O[c] + 1 NADP+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_14398
  • Source: annotation-in-silico_annotation
    • Assignment: AUTOMATED-NAME-MATCH
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_6196
  • Source: annotation-in-silico_annotation
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: Tiso_gene_15790
  • Source: annotation-in-silico_annotation
    • Assignment: AUTOMATED-NAME-MATCH

Pathways

• PWY-7765, 3-hydroxy-4-methyl-anthranilate biosynthesis II: PWY-7765
  • 2 reactions found over 5 reactions in the full pathway
• PWY-5651, L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde: PWY-5651
  • 4 reactions found over 5 reactions in the full pathway
• PWY-6309, L-tryptophan degradation XI (mammalian, via kynurenine): PWY-6309
  • 9 reactions found over 17 reactions in the full pathway
• PWY-7717, 3-hydroxy-4-methyl-anthranilate biosynthesis I: PWY-7717
  • 2 reactions found over 6 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 20545
• LIGAND-RXN:
  • R01960