RXN490-3641

Reaction RXN490-3641

• direction:
  • LEFT-TO-RIGHT
• common name:
  • proline,2-oxoglutarate-4-dioxygenase (cis-4-hydroxy-L-proline)
• ec number:
  • EC-1.14.11
• Synonym(s):
  • prolyl hydroxylase
  • prolyl 4-hydroxylase
  • proline,2-oxoglutarate 4-dioxygenase
  • proline hydroxylase
  • protocollagen hydroxylase

Reaction Formula

• With identifiers:
  • 1 2-KETOGLUTARATE[c] + 1 PRO[c] + 1 OXYGEN-MOLECULE[c] => 1 CARBON-DIOXIDE[c] + 1 SUC[c] + 1 4-HYDROXY-L-PROLINE[c]
• With common name(s):
  • 1 2-oxoglutarate[c] + 1 L-proline[c] + 1 oxygen[c] => 1 CO2[c] + 1 succinate[c] + 1 trans-4-hydroxy-L-proline[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_6296
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_16842
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_9636
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_3021
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_18689
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_15328
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_9035
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_13008
  • Source: orthology-athaliana
  • Source: orthology-creinhardtii
• Gene: Tiso_gene_15594
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_9873
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_18208
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_9455
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_16122
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_2158
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_17919
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_17823
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_18933
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_9227
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_18145
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_292
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_2280
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_1468
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_18235
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_19638
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_9165
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_17593
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_8652
  • Source: orthology-esiliculosus

Reconstruction information

• Category: orthology
  • Source: orthology-athaliana
    • Tool: pantograph
  • Source: orthology-creinhardtii
    • Tool: pantograph
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: manual
  • Source: manual-primary_network

External links

• LIGAND-RXN:
  • R01252